by Tokyo Metropolitan University Two different ways in which islet cell loss can be observed (top left and right) . The relationship between the percentage of pancreatic beta cells and islet cell loss (bottom left). The number of mild and severe cases of ICL at different ages (bottom right). Credit: Tokyo Metropolitan UniversityResearchers from Tokyo Metropolitan...
by Bob Yirka , Medical Xpress Overview of contributions. AMIE is a conversational medical AI optimized for diagnostic dialogue. AMIE is instruction fine-tuned with a combination of real-world and simulated medical dialogues, alongside a diverse set of medical reasoning, question self-play-based simulated dialogue environment with answering and summarization datasets. Notably, we designed a self-play based...
by UT Southwestern Medical Center Bioengineering and characterization of the immunosuppressive combinational colon-specific immune niche. Credit: Nature Biomedical Engineering (2023). DOI: 10.1038/s41551-023-01136-9By taking advantage of mechanisms that allow cancer cells to evade immune attack, UT Southwestern Medical Center researchers have developed a new strategy in animal models that has potential for treating ulcerative colitis. Their findings, reported...
by University of Freiburg A) UMAP projection of composite healthy donor (HD) samples from CD19+ cells of tonsil (n=7) and spleen (n=7) analyzed by spectral flow cytometry. (B) Identification of primary populations in one representative HD spleen and tonsil. (C) Identification of populations in the naïve B cell gate (IgD+CD38low). (D) Identification of populations within the...
by University of Eastern Finland Both total body fat mass and abdominal fat cause hyperglycemia, hyperinsulinemia, and insulin resistance, with abdominal fat doubling the risk of metabolic dysfunction. However, light physical activity can significantly reduce total body fat mass and insulin resistance. Credit: Andrew AgbajeHigh fat mass in adolescence causes insulin resistance, which can lead to...
by Erin Kayata, Northeastern University Credit: Fueled by Social Media, Gen Zers and Millennials Admit to Overspending on Beauty Products (2024). Over the holidays, Drunk Elephant skincare was a wish list mainstay, sending confused parents to beauty stores to puzzle over why their middle schoolers needed so many expensive products. The reason is social media, which...
by American College of Cardiology Credit: Unsplash/CC0 Public DomainPhosphodiesterase type 5 inhibitors (PDE5i)—an erectile dysfunction drug sold under the names Viagra, Levitra, Cialis, and others—are a common medical treatment for erectile dysfunction (ED) in men with cardiovascular disease (CVD). However, a new Swedish study published in the Journal of the American College of Cardiology suggests that...
by Sarah Avery, Duke University Pixabay/CC0 Public DomainWhile the risks of drug use, smoking and drinking during pregnancy are widely accepted, a new survey of parents has identified clear associations between certain types of childhood cancers and gestational substance use, notably cannabis. The study—led by Duke Health and appearing in the journal Cancer Epidemiology, Biomarkers, and...
by American College of Physicians Credit: Pixabay/CC0 Public DomainA population-based cohort study of more than 10,000 persons using gabapentinoids found that their use was associated with an increased risk of chronic obstructive pulmonary disease (COPD) exacerbation. This study supports the warnings from regulatory agencies and highlights the importance of considering this potential risk when prescribing gabapentin...
by Kerstin Wild, Leibniz Institute for Immunotherapy Wound healing and target killing are both effector mechanisms of CD8 T cells. (A) Combined proliferation and killing assay in the presence of influenza-specific CD8 T cells and varying amounts of pulsed peptides on MRC-5 and HaCaT cells seeded in a 30:70 ratio. Left, representative image with labels...
