by Ian Demsky, Memorial Sloan Kettering Cancer Center Schematic of the study design and analysis. a, Cohort collection. Top: a real-world cohort (MSK-I) from MSKCC was used for model development. Middle: two real-world cohorts from MSKCC (MSK-II) and MSHS were used. Bottom: 10 global phase 3 clinical trials were used. ITT, intention-to-treat. b, Feature selection analysis....
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Childhood smoking increases a person’s risk of developing COPD
Smoke exposure negatively impacts critical lung development in childhood and adolescencePeer-Reviewed Publication COPD Foundation Miami (January 7, 2025) – Childhood smoking before age 15 increases a person’s risk of developing chronic obstructive pulmonary disease (COPD), according to a new study. The study is published in the November 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the...
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Can you steam away prostate cancer?
Clinical trial offered by Keck Medicine of USC uses steam rather than surgery or radiation to potentially destroy cancer cells for certain prostate cancer patientsBusiness Announcement University of Southern California – Health Sciences image: Andre Abreu, MD, a Keck Medicine of USC urologist, performs a procedure using steam to destroy prostate cancer as part of...
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Mice use their tongues to ‘see’ tactile targets: Neural pathway discovery could help treat neurological disorders
by Kate Blackwood, Cornell University Credit: Unsplash/CC0 Public Domain Chewing a bagel while reading the morning news, speaking while driving, dislodging a piece of food stuck between two teeth: In these and other tasks, the tongue and the brain coordinate intricate movements without conscious attention, but the exact pathway in the brain has been largely unexplored....
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Computer simulations detail ‘protein clumps’ linked to Huntington’s disease
by University of Bergen Visualization of protein clumps associated with Huntington’s disease, produced by combining simulations and several complementary types of experiments. Credit: Markus Miettinen, UiB/CBU. University of Bergen researcher Markus Miettinen is among the first scientists to provide a detailed description of protein clumps associated with Huntington’s disease. The findings, which could pave the way...
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Bile acids’ surprising role in food allergy treatment revealed
by Brittany Phillips, University of North Carolina at Chapel Hill School of Medicine Conclusions. Credit: Pediatric Allergy and Immunology (2024). DOI: 10.1111/pai.14267 Metabolites—small molecules within cells, biofluids, tissues or organisms—play an integral role in various diseases, and studying the many metabolites (metabolomics) can teach us how the body works in ways that help researchers develop new treatments, especially...
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Discovery of immune-boosting fibroblasts offers hope for cancer patients
by University of Southampton Schematic of Pan-Cancer Fibroblast Atlas (PCFA) including anatomical sites, sample/fibroblast numbers and original publications. Credit: Molecular Cancer (2025). DOI: 10.1186/s12943-024-02191-9 Southampton scientists working to improve survival for cancer patients have identified a key characteristic of the disease that could make treatment more effective. The aim of the University of Southampton study is for patients...
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Loneliness linked to proteins that may increase disease risk and mortality
by Barbara Jacquelyn Sahakian, Christelle Langley, Chun Shen, Jianfeng Feng, The Conversation Credit: Unsplash/CC0 Public Domain Human beings are inherently social. We thrive on connection, communication and shared experiences, which help shape our identities and foster a sense of belonging. Yet, in an increasingly digital and fast-paced world, feelings of loneliness and social isolation have become...
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Why seeing the same doctor could save your life
by James Goodwin, The Conversation Credit: Pixabay/CC0 Public Domain Seeing the same GP each time has its advantages, and it is more important than it may seem. A milestone review examining 1.4 million patients worldwide found that those who do not see the same doctor regularly are more likely to die within a certain period. This consistent relationship...
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Biolasers light up circulating tumor cells in the bloodstream
by Ananya Sen, University of Michigan The stained cancer cells are sandwiched between two mirrors and an excitation laser is shone at them one cell at a time. Credit: Jacob Dwyer, Michigan Medicine Researchers from the University of Michigan have developed a way of detecting circulating tumor cells in the bloodstream of pancreatic cancer and lung...