by Chen Na, Chinese Academy of Sciences Analysis revealed that astrocytes transdifferentiated into oligodendrocytes following SCI. A, B. Monocle, RNA velocity analyses of astrocytes, OPCs, maturing oligodendrocytes, and myelination oligodendrocyte population. C. Immunofluorescence images showing co-localization of SOX9, SOX10 and GFAP. D, E. lineage tracing demonstrated ALDH1L1-traced cells expressing MAG in the spinal cord before and...
Year: <span>2025</span>
Post
Pertussis cases surging in the United States
by Physician’s Briefing Staff Rates of pertussis in the United States are surging, with more than 32,000 cases reported as of mid-December—about six times more than at this time last year and more than have been reported since 2014, according to data from the U.S. Centers for Disease Control and Prevention. Reported cases have been climbing...
Post
New AI tool uses routine blood tests to predict immunotherapy response for many cancers
by Ian Demsky, Memorial Sloan Kettering Cancer Center Schematic of the study design and analysis. a, Cohort collection. Top: a real-world cohort (MSK-I) from MSKCC was used for model development. Middle: two real-world cohorts from MSKCC (MSK-II) and MSHS were used. Bottom: 10 global phase 3 clinical trials were used. ITT, intention-to-treat. b, Feature selection analysis....
Post
Childhood smoking increases a person’s risk of developing COPD
Smoke exposure negatively impacts critical lung development in childhood and adolescencePeer-Reviewed Publication COPD Foundation Miami (January 7, 2025) – Childhood smoking before age 15 increases a person’s risk of developing chronic obstructive pulmonary disease (COPD), according to a new study. The study is published in the November 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the...
Post
Can you steam away prostate cancer?
Clinical trial offered by Keck Medicine of USC uses steam rather than surgery or radiation to potentially destroy cancer cells for certain prostate cancer patientsBusiness Announcement University of Southern California – Health Sciences image: Andre Abreu, MD, a Keck Medicine of USC urologist, performs a procedure using steam to destroy prostate cancer as part of...
Post
Mice use their tongues to ‘see’ tactile targets: Neural pathway discovery could help treat neurological disorders
by Kate Blackwood, Cornell University Credit: Unsplash/CC0 Public Domain Chewing a bagel while reading the morning news, speaking while driving, dislodging a piece of food stuck between two teeth: In these and other tasks, the tongue and the brain coordinate intricate movements without conscious attention, but the exact pathway in the brain has been largely unexplored....
Post
Computer simulations detail ‘protein clumps’ linked to Huntington’s disease
by University of Bergen Visualization of protein clumps associated with Huntington’s disease, produced by combining simulations and several complementary types of experiments. Credit: Markus Miettinen, UiB/CBU. University of Bergen researcher Markus Miettinen is among the first scientists to provide a detailed description of protein clumps associated with Huntington’s disease. The findings, which could pave the way...
Post
Bile acids’ surprising role in food allergy treatment revealed
by Brittany Phillips, University of North Carolina at Chapel Hill School of Medicine Conclusions. Credit: Pediatric Allergy and Immunology (2024). DOI: 10.1111/pai.14267 Metabolites—small molecules within cells, biofluids, tissues or organisms—play an integral role in various diseases, and studying the many metabolites (metabolomics) can teach us how the body works in ways that help researchers develop new treatments, especially...
Post
Discovery of immune-boosting fibroblasts offers hope for cancer patients
by University of Southampton Schematic of Pan-Cancer Fibroblast Atlas (PCFA) including anatomical sites, sample/fibroblast numbers and original publications. Credit: Molecular Cancer (2025). DOI: 10.1186/s12943-024-02191-9 Southampton scientists working to improve survival for cancer patients have identified a key characteristic of the disease that could make treatment more effective. The aim of the University of Southampton study is for patients...
Post
Loneliness linked to proteins that may increase disease risk and mortality
by Barbara Jacquelyn Sahakian, Christelle Langley, Chun Shen, Jianfeng Feng, The Conversation Credit: Unsplash/CC0 Public Domain Human beings are inherently social. We thrive on connection, communication and shared experiences, which help shape our identities and foster a sense of belonging. Yet, in an increasingly digital and fast-paced world, feelings of loneliness and social isolation have become...