A steroid jab in the bottom could ease hip pain caused by osteoarthritis for up to 12 weeks

Home / Pharmaceutical Updates / A steroid jab in the bottom could ease hip pain caused by osteoarthritis for up to 12 weeks
  • The steroid injection was trialled by researchers in the Netherlands
  • Relief period matched that of steroid injections directly into the affected joint
  • The buttock jab is much less painful and can be administered by GPs
  • An estimated nine million people in Britain have some degree of osteoarthritis

A single steroid injection to the buttocks could banish hip pain caused by osteoarthritis for up to 12 weeks

A single steroid injection to the buttocks could banish hip pain caused by osteoarthritis for up to 12 weeks

A jab in the buttocks could be a new way to banish hip pain caused by osteoarthritis.

A single steroid injection into the muscles in the bottom gave volunteers pain relief for up to 12 weeks in a trial in the Netherlands.

This matched the duration of relief seen with standard steroid injections directly into the affected joint.

The problem with these is that they can be painful and normally have to be administered by a specialist in hospital, using X-ray or ultrasound images to make sure the steroid is targeted at the most damaged part of the hip.

The big advantage of a buttock jab is it’s less painful (as the injection goes into muscle, which is softer) and easier to perform, so they can be given by GPs in their surgery.

An estimated nine million people in Britain have some degree of osteoarthritis. As the body ages, major joints such as the hips, knees and wrists suffer wear and tear.

Other risk factors include being overweight, having a family history of the condition and sports injuries.

Normally, cartilage absorbs the impact from walking, running or lifting, so bones do not rub together. But in osteoarthritis, the cartilage starts to break down and as bones come into contact, the friction makes them swollen and extremely painful.

many arthritis patients rely on anti-inflammatory painkillers. However, while these help, they can damage the stomach lining if used for a long time, potentially leading to stomach ulcers and internal bleeding

More than 100,000 people a year in England alone end up having hip replacement surgery on the NHS because their joints are so badly eroded.

Steroid injections are widely used to dampen down inflammation in the joint that causes excruciating pain. But they often have to be repeated because the effects wear off after a few months.

Smaller joints such as wrists and knees can be injected by a GP under a local anaesthetic. But injecting larger joints such as hips is more complex and carries a small risk of septic arthritis — an infection in the joint.

Researchers at the Erasmus Medical Centre in Rotterdam recruited 107 patients with painful hip arthritis. Half were given a dummy jab containing salt water into the buttocks.

The big advantage of a buttock jab is it’s less painful (as the injection goes into muscle, which is softer) and easier to perform, so they can be given by GPs in their surgery

The big advantage of a buttock jab is it’s less painful (as the injection goes into muscle, which is softer) and easier to perform, so they can be given by GPs in their surgery

The other half were injected with 40mg of triamcinolone acetate, a type of steroid widely used on the NHS.

The average pain rating, on a scale of one to ten, was 4.3 before the injections. After two weeks, the rating by those given the steroid jab had dropped to 2.6, compared with 3.9 in the placebo group. They enjoyed 12 pain-free weeks until their scores increased.

Researcher Dr Desiree Dorleijn said the next step is to see if the technique of injecting muscles rather than joints could benefit other parts of the body affected by cartilage destruction.

Dr Fraser Birrell, a consultant rheumatologist from the charity Arthritis Care, was part of a team that pioneered hip injections of steroids. Commenting on the new research, he said: ‘This is an interesting study. It’s the first to show injecting the muscle can be effective for up to 12 weeks.

‘We have to be cautious until the full results are published in a medical journal. But if the findings are replicated in another study it would certainly become an option for patients.’

Meanwhile, a vaccine to treat osteoarthritis is a step closer thanks to a breakthrough using stem cells.

Scientists at Washington University ‘rewired’ stem cells taken from the tails of mice, removing a key gene that causes inflammation, and replacing it with a gene that releases a natural drug to combat inflammation.

It’s hoped this drug will eventually be able to replace arthritic cartilage and also protect other joints from damage.

Snoring? It may be sleep groaning!

Groaning during sleep is much more common than previously thought, say researchers from the University of California, but goes under-recognised as it can be confused with snoring.

The condition, also known as catathrenia, is louder, occurring on exhaling, causing the vocal cords to vibrate, while snoring usually happens when you inhale.

Groaning during sleep is much more common than previously thought

Groaning during sleep is much more common than previously thought

Groans can last up to 50 seconds and occur many times a night.

As well as embarrassment, it can cause fatigue and depression in sufferers (typically male) and their partners.

Yoga or exercises for the facial muscles might help and should be further investigated, the researchers said.

Can a cold trigger chronic anxiety?

Anxiety and panic attacks may be triggered by inflammation in the body.

Research in the journal Psychosomatic Medicine found that in people with panic disorder (recurring panic attacks), levels of interleukin-6, a compound associated with inflammation, are a third higher.

The study from Federal University of Rio Grande do Sul, Brazil, is the latest to investigate possible biological causes of psychiatric conditions.

This follows observations that patients with inflammatory diseases, such as rheumatoid arthritis, have higher rates of depression.

One theory is the inflammation may start with an infection, such as a cold, or poor diet.

Fluorescent dye test that could save sight

A new test could diagnose glaucoma early and stop patients losing their sight. Glaucoma occurs when the drainage tubes in the eye are blocked; the build-up of fluid and pressure damages the optic nerve.

The problem is it’s largely symptomless until patients lose their vision. The new test involves injecting fluorescent dye into the patient’s arm — this contains a protein that sticks to dying nerve cells and shows up as white spots on an eye scan.

A study by Western Eye Hospital, part of Imperial College London, showed white spots were more common in people with glaucoma and increased as it worsened.

Viagra may help men live longer after a heart attack 

Do drugs for erectile dysfunction help men who have had a heart attack to live longer?

Viagra could lower the risk of heart failure through their effect on blood flow

Viagra could lower the risk of heart failure through their effect on blood flow

That’s the suggestion from Swedish research published in the journal Heart. Involving more than 43,000 men, it found that six years after a heart attack, just 3.7 per cent of men on drugs for erectile dysfunction (such as sildenafil, the generic name for Viagra, which works by improving blood flow to the penis) had died, compared with 12 per cent of men not taking the medication.

The theory is that the drugs lowered the risk of heart failure through their effect on blood flow.