Considerable time has been spent by scientists in analyzing the cause of Chronic Fatigue Syndrome (CFS) or Myalgic Encephalomyelitis. The puzzle, however, persisted without any clue whether it was a psychological or physical illness. There are one million Americans affected by this disease. Complete exhaustion makes people afflicted with CFS incapacitated to work or study. The underlying...
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Pitt study provides clues to relationship between schizophrenia and rheumatoid arthritis
PITTSBURGH, Feb. 24, 2017 – An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at lower risk for the other, according to the results of a...
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Absent tumor-suppressors allow melanoma to thwart immunotherapy
Researchers identified a set of genetic changes that predict whether melanoma patients will respond to checkpoint inhibitor therapies. It’s what’s missing in the tumor genome, not what’s mutated, that thwarts treatment of metastatic melanoma with immune checkpoint blockade drugs, researchers at The University of Texas MD Anderson Cancer Center report in Science Translational Medicine. Whole...
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A new role for an old immune cell may lead to novel therapies for infection and cancer
A new study has identified a previously undescribed role for a type of unconventional T cell with the potential to be used in the development of new therapies for infection and cancer. The study, published today in Nature Communications, shows that Gamma Delta T cells are able to generate immunological memory against previous infections and cancerous...
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Snail venom could knock out pain – and opioid addiction
With an epidemic of addiction to opioid painkillers on the rise, researchers say they’ve found an alternative for pain relief from an unlikely source – a small snail found in the Caribbean Sea. Scientists from the University of Utah say the little cone snail Conus regius produces a venom that blocks a pain pathway different from the...
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Are ibuprofen and aspirin the cures for sepsis? Similar drugs found to prevent blood poisoning which kills thousands
Sepsis is a life-threatening inflammatory response to an infection, doctors say NSAIDs work by blocking an enzyme in the body that causes inflammation But scientists found they can also inhibit another enzyme responsible for it Sepsis can rob someone of their life in minutes. But a potentially life-saving treatment has been under our noses for...
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The stem cell dynamics of wound healing
Researchers at the Université libre de Bruxelles, ULB define for the first time the changes in the stem cell dynamics that contribute to wound healing. One of the key questions in biology is to identify how tissues are repaired after trauma and understand how stem cells migrate, proliferate, and differentiate to repair tissue damage. In a study...
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From Alzheimer’s to autism, nuclear neurology could launch revolution in diagnosing and treating brain diseases
Image of glucose metabolism PET overlaid on CT in an Alzheimer’s patient with mild dementia. Green arrow points to regional hypometabolism in the medial parietal lobe, (which processes biographical information and memory),a proposed biomarker for Alzheimer’s. UB researcher with database of 16,000 brain scans proposes that powerful imaging can transform neurology as it did cardiology...
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Discovery could help doctors to spot cardiovascular disease at an earlier stage
Screening methods for cardiovascular diseases such as heart attacks and strokes could be improved by measuring different biological signposts to those currently being tested, a new study led by researchers from King’s College London suggests. Published in the Journal of the American College of Cardiology, the study could allow doctors to better predict the development of...
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Scientists spot signs that predict worsening multiple sclerosis
(HealthDay)—Multiple sclerosis (MS) is more likely to progress to advanced disease among patients who suffer from fatigue and limited use of their legs, new research suggests. “Better understanding who is at high risk of getting worse may eventually allow us to tailor more specific treatments to these people,” said study author Dr. Bianca Weinstock-Guttman. She...