Liam McNicholas, 12, of Lindenhurst, talks with Meghan Kostyk, an advanced practice nurse, on Feb. 9, 2017, during his biannual visit to Lurie Children’s Hospital for a checkup. Liam has Duchenne muscular dystrophy, a condition which is treated by a drug from a Northbrook company that just received FDA approval. (Alyssa Pointer / Chicago Tribune)...
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Common weed could help fight deadly superbug, study finds
Cassandra Quave, an ethnobotanist at Emory University, in her lab with berries from the Brazilian peppertree. The red berries of a weed found in the southern United States contain an compound that can disarm a deadly superbug, according to research published Friday. Researchers from Emory University and the University of Iowa found that extracts...
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Could depression be treated with Botox?
In the largest randomized, double-blind, placebo controlled study to date on the effect of OnabotulinumtoxinA (as known as Botox) on depression, researchers found that more than half of subjects suffering from moderate to severe depression showed a substantial improvement (greater than or equal to 50% of baseline) in their depressive symptoms as measured by the...
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Prion Test For Rare, Fatal Brain Disease Helps Families Cope
Keith Negley for NPR By the time Kay Schwister got her diagnosis last summer, she couldn’t talk anymore. But she could still scowl, and scowl she did. After weeks of decline and no clue what was causing it, doctors had told Schwister — a 53-year-old vocational rehab counselor and mother of two from Chicago —...
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First blood biomarker for multiple sclerosis discovered
A blood test for determining the subtype of MS could be as little as two years away following the discovery of a blood biomarker Although there is no known cure for multiple sclerosis (MS), there are treatments that can help prevent new attacks and improve function after an attack. However, there are three subtypes of...
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Researchers chart global genetic interaction networks in human cancer cells
Using genome-wide CRISPR screens, Wang et al. identified clusters of genes that act together to carry diverse sets of biological processes that support cell survival and proliferation Cancer is a heterogeneous disease, with myriad distinct subtypes that differ in their genetic roots. As a result, cancers rely on varied pathways for survival — and respond...
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Scientists identify two brain networks influencing how we make decisions
Scientists at the Medical Research Council Brain Network Dynamics Unit at the University of Oxford have pinpointed two distinct mechanisms in the human brain that control the balance between speed and accuracy when making decisions. Their discovery, published in eLife, sheds new light on the networks that determine how quickly we choose an option, and how...
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The number of microvascular complications is associated with an increased risk for severity of periodontitis in type 2 diabetes patients: Results of a multicenter hospital‐based cross‐sectional study
Abstract Aims/Introduction To explore the relationships between periodontitis and microvascular complications as well as glycemic control in type 2 diabetes patients. Materials and Methods This multicenter, hospital‐based, cross‐sectional study included 620 patients with type 2 diabetes. We compared the prevalence and severity of periodontitis between patients with ≥1 microvascular complication and those without microvascular complications....
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Study of complex genetic region finds hidden role of NCF1 in multiple autoimmune diseases
IMAGE: BETTY PEI-TIE TSAO, PH.D., IS THE RICHARD M. SILVER ENDOWED CHAIR FOR INFLAMMATION RESEARCH AT THE MEDICAL UNIVERSITY OF SOUTH CAROLINA AND SENIOR AUTHOR ON THE NATURE GENETICS ARTICLE…. view more Investigators at the Medical University of South Carolina (MUSC) report pre-clinical research showing that a genetic variant encoded in neutrophil cystolic factor 1 (NCF1) is associated with...
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T cell type that promotes damaging immune response discovered
For the first time, researchers have identified a type of T cell that plays a key role in promoting the damaging autoimmune response that inflames and attacks the joints in rheumatoid arthritis. The discovery – made with technologies that help to analyze just a “handful of cells” – offers vital new clues to the biology...