By Matthew Herper Marc, a 62-year-old who has had Parkinson’s for 30 years, received an experimental treatment that appeared to notably improve his ability to keep his balance and walk without freezing up. An experimental treatment that delivers an electrical current to the spinal cord appeared to notably improve the ability of a man with Parkinson’s...
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Researchers find the roots of tau tangles in Alzheimer’s disease
by Bill Hathaway, Yale University Credit: Pixabay/CC0 Public Domain An experimental drug can reduce the toxic changes in tau proteins known to damage neurons in brains with Alzheimer’s disease, researchers from Yale School of Medicine and Johns Hopkins University report. While much research related to Alzheimer’s disease has concentrated on identifying ways to reduce the buildup...
Ask the pediatrician: How to talk with your child about the Israel-Gaza war
by David Schonfeld, MD, FAAP, American Academy of Pediatrics Credit: Pixabay/CC0 Public Domain The Israel-Gaza war is distressing, and children and teens may be wondering why this violence is occurring and what else will happen in the future. Like adults, they are better able to cope with upsetting news and images when they understand more...
Prediabetes and persistent tobacco use may triple risk of stroke in healthy young adults
by American Heart Association Credit: CC0 Public Domain The combination of persistent tobacco use and prediabetes (higher than normal blood sugar levels that may progress to type 2 diabetes) triples the risk of stroke in young adults who do not have other cardiovascular risk factors, according to a preliminary study presented at the American Heart Association’s...
Future therapies for managing inflammatory bowel disease
Peer-Reviewed Publication FIRST HOSPITAL OF JILIN UNIVERSITY ANTITUMOUR NECROSIS FACTOR ALPHA (ANTI-TNFΑ) AGENTS INCLUDE INFLIXIMAB, ADALIMUMAB, GOLIMUMAB, AVX-470 AND OPRX-106. JANUS KINASE (JAK) INHIBITORS: TOFACITINIB, FILGOTINIB AND UPADACITINIB. CYTOKINE INHIBITORS: USTEKINUMAB, WHICH TARGETS INTERLEUKIN (IL) 12, SUBUNIT P40/P35; RISANKIZUMAB, MIRIKIZUMAB, GUSELKUMAB AND BRAZIKUMAB TARGET IL-23, SUBUNIT P40/P19. SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS: AMISELIMOD, OZANIMOD, ETRASIMOD AND...
Carbon-based sensors are poised to facilitate a seamless human-machine interface
Peer-Reviewed Publication TSINGHUA UNIVERSITY PRESS SMALL, COMFORTABLE GRAPHENE SENSORS CAN MEASURE A VARIETY OF BODILY SIGNALS, INCLUDING RESPIRATIONS, VOCALIZATIONS, TEMPERATURE AND GESTURES, THROUGH TESTS SUCH AS ELECTROENCEPHALOGRAMS (EEGS) THAT QUANTIFY BRAIN WAVES AND ELECTROOCULOGRAMS (EOCS) THAT MEASURE EYE MOVEMENT. CREDIT: CARBON FUTURE, TSINGHUA UNIVERSITY PRESS Interaction between machines and humans is paramount to the development...
Nasal microorganism to the rescue? Study confirms protective role of bacterium in chronic rhinosinusitis
Scientists investigate how microbes in the nasal mucosa may influence the pathophysiology of chronic sinusitis Peer-Reviewed Publication UNIVERSITY OF FUKUI EXPERIMENTS CONDUCTED IN A RECENT STUDY BY RESEARCHERS FROM JAPAN SUGGEST THAT THE LIPOPOLYSACCHARIDES (LPS) PRODUCED BY THE BACTERIAL SPECIES F. NUCLEATUM SUPPRESSES THE EXPRESSION OF ALOX15 AND PREVENTS EXCESSIVE INFILTRATION OF EOSINOPHILS, WHICH CAUSES...
Incheon National University scientists develop new hydrogels for wound management
By leveraging the power of oxygen, these gelatin patches can act as effective tissue adhesives that accelerate the healing of woundsPeer-Reviewed Publication INCHEON NATIONAL UNIVERSITY Hydrogels are a promising approach for treating wounds. CONVENTIONAL WOUND MANAGEMENT TECHNIQUES LIKE SUTURE AND STAPLING HAVE SEVERAL DRAWBACKS. TISSUE ADHESIVE PATCHES MADE FROM HYDROGELS COULD BE A GOOD ALTERNATIVE...
Physicists overturn common assumptions regarding brain activity
New types of experiments indicate that many neuronal features commonly attributed to the soma originate from dendritic mechanisms could impact research of the origin of degenerative diseases, and sleep and awake states of brain activity.Peer-Reviewed Publication BAR-ILAN UNIVERSITY A PARADIGM SHIFT IN BRAIN RESEARCH: THE NEW NEURON AND THE NEW TYPE OF LEARNING – CONTNIUE....
Shorter white blood cell telomeres linked to higher dementia risk
Peer-Reviewed Publication SHANGHAI JIAO TONG UNIVERSITY JOURNAL CENTER SHORTER LTL IS ASSOCIATED WITH TOTAL AND REGIONAL BRAIN STRUCTURE AND A HIGHER RISK OF INCIDENT DEMENTIA AND AD, IMPLYING THE POTENTIAL OF TELOMERE LENGTH AS A PREDICTIVE BIOMARKER OF BRAIN HEALTH. CREDIT: ZHI CAO ET AL. Shorter telomeres on the ends of white blood cell chromosomes...