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Previous genetic association studies involving people with European ancestry may be inaccurate
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Previous genetic association studies involving people with European ancestry may be inaccurate

by NIH/National Human Genome Research Institute Researchers have found that previous studies analyzing the genomes of people with European ancestry may have reported inaccurate results by not fully accounting for population structure. Credit: Darryl Leja, National Human Genome Research Institute Researchers have found that previous studies analyzing the genomes of people with European ancestry may have...

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Beware of Popular Online Liver Supplements, Doctors Say

Damian McNamara, MA November 06, 2023 The 10 best-selling liver health supplements on Amazon bring in an estimated $2.5 million each month. But none of them contain ingredients recommended by major groups of doctors who treat liver issues in the United States or Europe. Like many supplements, popular online liver products are unregulated, meaning they...

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mRNA’s next trick? Reprogramming off-the-shelf cell therapies for cancer and autoimmune diseases

mRNA’s next trick? Reprogramming off-the-shelf cell therapies for cancer and autoimmune diseasesRyan CrossSenior Science CorrespondentLei Lei WuNews ReporterA handful of biotechs, including Moderna, are betting that simple infusions with mRNA could supercharge immune cells to fight cancer and other diseases in what would be a fresh take on CAR-T cell therapies.Instead of collecting a patient’s...

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New study projects continued rise in most common liver disease

Liver doctors change how they talk about liver disease as cases climb Reports and Proceedings AMERICAN ASSOCIATION FOR THE STUDY OF LIVER DISEASES Boston (Nov. 7, 2023) — The most common form of chronic liver disease is expected to steadily rise over the next 25 years, adding significant burden to the medical system as a...

Pancreas ‘crosstalk’ may influence course of type 1 and type 2 diabetes
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Pancreas ‘crosstalk’ may influence course of type 1 and type 2 diabetes

by Bill Snyder, Vanderbilt University Method for quantification of ADM lobules. ADM-positive lobules (outlined in green) were tallied per section. Total pancreatic tissue (orange) was outlined manually and quantified. ADM score was determined by dividing the total number of ADM-positive lobules (across head, body, and tail regions) by the total tissue area. Scale bar = 2mm....

Boosting immune system in chronic myeloid leukemia may lead to discontinuation of blood cancer drugs
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Boosting immune system in chronic myeloid leukemia may lead to discontinuation of blood cancer drugs

by University of Helsinki Schematics showing the overview of data sets, analysis, and validation and extensions. Picture created with biorender.com. Credit: Leukemia (2023). DOI: 10.1038/s41375-023-02074-w In a recent study published in Leukemia, Finnish researchers investigated why some patients with chronic myeloid leukemia (CML) can discontinue their daily medication safely. CML, one of the four main types...

Understanding that chronic back pain originates from within the brain could lead to quicker recovery, study finds
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Understanding that chronic back pain originates from within the brain could lead to quicker recovery, study finds

by Yoni Ashar, The Conversation Credit: Pixabay/CC0 Public Domain Most people with chronic back pain naturally think their pain is caused by injuries or other problems in the body such as arthritis or bulging disks. But our research team has found that thinking about the root cause of pain as a process that’s occurring in the...

Antireflux mucosal ablation safe, effective for refractory reflux disease
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Antireflux mucosal ablation safe, effective for refractory reflux disease

by Lori Solomon Antireflux mucosal ablation (ARMA) cuts short-term gastroesophageal reflux disease (GERD) symptoms in two-thirds of patients undergoing the endoscopic treatment, according to a study published in the Journal of Gastroenterology and Hepatology. Yuto Shimamura, M.D., from Showa University in Tokyo, and colleagues evaluated the feasibility, safety, and effectiveness of ARMA. The analysis included...

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Each nostril has a unique sense of smell, intracranial electroencephalogram study finds

by Justin Jackson , Medical Xpress Credit: Unsplash/CC0 Public Domain Research led by the University of Pennsylvania, Philadelphia, and the Barrow Neurological Institute, Phoenix, has examined the neural processes underlying odor processing in the human olfactory system and how the brain handles odor information from different nostrils. In a new paper titled “Odor representations from...

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Attacking the roots of pancreatic cancer

by Alan Dove, Columbia University Irving Medical Center The new model provides a unique opportunity to understand how adenosquamous tumors, which are essentially unresponsive to current treatments, arise in the pancreas. In the new study, the researchers found that Hmmr gene activity is important for the growth of ASCP tumors and could be a new therapeutic...