by Higher Education Press Manganese therapy enables the reversal of atherosclerotic plaque. Credit: Yawei Wang, Xin Feng, Wenjing Zhou, Runze Huang, Yating Hu, Hui Hui, Jie Tian, Xiao Wang, Xiao-Wei Chen Cardiovascular disease (CVD) continue to rank as the top killer in the modern world. This deadly disorder often starts with the buildup of lipid...
by University of Chicago Medical Center Credit: Cell Reports Medicine (2023). DOI: 10.1016/j.xcrm.2023.101261 Type 1 diabetes is an autoimmune disease that causes the body’s immune system to attack and destroy insulin-producing beta cells in the pancreas. Traditional management of type 1 diabetes has primarily involved replacing the missing insulin with injections which, though effective, can be...
by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Credit: Cell (2023). DOI: 10.1016/j.cell.2023.10.001 Researchers at DZNE and Charité–Universitätsmedizin Berlin have pioneered a novel treatment for the most common autoimmune encephalitis. By reprogramming white blood cells to target and eliminate disease-causing cells, the approach offers a new level of precision and efficiency. The technique...
by Duke-NUS Medical School Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.08.001 Scientists from Duke-NUS Medical School, in collaboration with counterparts from Columbia University, have developed a new framework to measure metabolic health. The concept of “metabolic elasticity” paints a more comprehensive picture of how the body reacts to changes in the availability of food and how efficiently...
by Chinese Academy of Sciences Retrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIAT Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and their collaborators have developed a gene therapy strategy to selectively manipulate Parkinson’s disease-affected circuitry and attenuate the core motor symptoms...
by Korea University College of Medicine LHb D-neurons project to RMTg GABAergic neurons and are activated by acute stress. Acute stress evokes trace amine release from LHb D-neurons to RMTg GABAergic neurons, leading to neuronal inactivation via TAAR1-mediated trace aminergic signaling. As the effect of trace amines overrides the excitatory glutamatergic transmission, LHb D-neurons act...
By Jennifer Rigby October 23, 2023 (Reuters) – A pill for dengue fever developed by Johnson & Johnson appeared to protect against a form of the virus in a handful of patients in a small human challenge trial in the United States, according to data presented by the company on Friday. There are currently no specific treatments...
Courtney Southwick October 23, 2023 Exercising for at least 30 minutes three times a week can be just as effective as Viagra and similar medications at improving erectile function, according to a new analysis of the best research to date on aerobic exercise and erectile function. The study, published this month in The Journal of Sexual Medicine,...
Liam Davenport October 12, 2023 Electrodermal activity (EDA) measured via a smart bracelet/wristband may help predict and track changes in mood and more rapidly assess treatment response in patients with bipolar disorder (BD), early research suggests. In a small observational pilot study, researchers found the E4 wristband (Empatica, Inc) was able to detect fluctuations in mood. The...
Google looks to ultrasound to monitor heart rate through ANC headphonesBy Paul RiddenOctober 31, 2023 Google researchers have developed a system that can transform any TWS ANC wearables into heart rate monitors via a software updateSmartwatches that can monitor a wearer’s heart rate use light pulses to detect changes in blood volume. But research from...
