by Charles University Immune response to SFB bacteria in the intestines. Credit: Katarína Kováčová Researchers from the Jan Dobeš laboratory at Charles University in Prague have made a significant discovery uncovering a novel immune response in the intestinal epithelium. Furthermore, their study delineates a mechanism that controls this immune response. Their findings were recently published in...
by Cleveland Clinic B-COBRA HA antigens for the vaccination and infection of pre-immune ferrets. Credit: Scientific Reports (2023). DOI: 10.1038/s41598-023-43003-2 Recent preclinical results indicate novel next-generation vaccine candidates developed at Cleveland Clinic protect against multiple strains of influenza and last longer than vaccines currently in use. The vaccines are part of Cleveland Clinic’s global vaccine research...
Alok Patel, MD DISCLOSURES August 01, 2023 Alok S. Patel, MD: A friend recently joked with me and said, “I wish you were a dermatologist so you could hook me up with Botox and fillers.” Well, little does this friend know that I could be a certified cosmetic injector just after a weekend course. Botox parties, here...
Marilynn Larkin October 30, 2023 Studies have shown links between statin use and type 2 diabetes (T2D) for more than a decade. A US Food and Drug Administration label change for the drugs warned in 2012 about reports of increased risks of high blood glucose and glycosylated hemoglobin (A1c) levels. However, in the same warning, the FDA...
Marilynn Larkin October 26, 2023 TOPLINE: Serum vitamin D levels are significantly lower and the prevalence of vitamin D deficiency is significantly higher in patients with ulcerative colitis (UC) compared with controls, although a causal relationship cannot be demonstrated. METHODOLOGY: TAKEAWAY: SOURCE: Yan Wang, PhD, Department of Gastroenterology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an,...
Mitchel L. Zoler, PhD October 26, 2023 TOPLINE: Among the 3188 people with type 2 diabetes who were adherent to their tirzepatide (Mounjaro, Lilly) regimen in four pivotal trials of the agent, a quarter achieved at least a 15% cut from their baseline body weight after 40–42 weeks of treatment, and researchers found seven baseline variables that...
by Cara Murez Americans have been getting COVID treatments such as Paxlovid for free, but that’s about to end. The medications will enter the private market this week, the Associated Press reported. The price for a five-day course of Paxlovid, made by Pfizer, will be $1,390. Merck has not confirmed a price for its COVID...
by Okayama University A recent study by Okayama University researchers found that short-chain fatty acids produced by intestinal bacteria trigger the extension of the dendrites of dendritic cells by inhibiting an enzyme known as histone deacetylase. This results in a stonger immune response. Credit: Dr. Kazuyuki Furuta from Okayama University, Japan Dendritic cells play a key...
by Elana Gotkine Testosterone replacement therapy (TRT) is efficacious for correcting anemia among middle-aged and older men with hypogonadism and anemia, according to a study published online Oct. 27 in JAMA Network Open. Karol M. Pencina, Ph.D., from Brigham and Women’s Hospital in Boston, and colleagues examined the efficacy of TRT for correcting anemia in...
Kristin Canning October 20, 2023 A new artificial intelligence (AI) model can detect the deadliest skin cancer with 100% accuracy, highlighting the rapid improvement of AI in medicine, say researchers from the UK. AI detected more than 99% of all skin cancers. The researchers tested the AI by integrating it into a clinical diagnosis process ― anticipating...
