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Lymphoid reaction observed in eczema patients receiving dupilumab
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Lymphoid reaction observed in eczema patients receiving dupilumab

by Elana Gotkine For adults with atopic dermatitis (AD) receiving dupilumab treatment, a reversible lymphoid reaction (LR) has been observed, which mimics cutaneous T-cell lymphoma (CTCL), according to a study published online Oct. 18 in JAMA Dermatology. Celeste M. Boesjes, M.D., from the University Medical Center Utrecht in the Netherlands, and colleagues conducted a retrospective...

SARS-CoV-2 infection affects energy stores in the body, study shows
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SARS-CoV-2 infection affects energy stores in the body, study shows

An international research team, including Jonathan C. Schisler, PhD, in the UNC School of Medicine, has found how SARS-CoV-2 causes widespread “energy outages” throughout major organs, and how these effects contribute to debilitating long COVID sympto Peer-Reviewed Publication UNIVERSITY OF NORTH CAROLINA HEALTH CARE JONATHAN C. SCHISLER, PHD CREDIT: UNC DEPARTMENT OF PHARMACOLOGY CHAPEL HILL,...

The first oncogene was found more than 40 years ago. CNIO researchers have just discovered that it has a previously unknown mechanism of action
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The first oncogene was found more than 40 years ago. CNIO researchers have just discovered that it has a previously unknown mechanism of action

Peer-Reviewed Publication CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) FROM LEFT TO RIGHT: IVÁN PLAZA-MENACHO, SENIOR AUTHOR, AND FIRST AUTHORS JULIA CONTRERAS AND HIPÓLITO NICOLÁS CUESTA HERNÁNDEZ.view more CREDIT: ESTHER SÁNCHEZ / CNIOIn the late 1970s, the relationship between the c-Src gene and cancer was discovered. The first oncogene was identified.Since then, c-Src has been found...

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Hair Follicle Regression may be Driven by Cell-to-Cell Apoptosis

Reviewed by Lily Ramsey, LLMOct 24 2023 A new research paper was published in Oncotarget’s Volume 14 on October 19, 2023, entitled, “Apoptotic cells may drive cell death in hair follicles during their regression cycle.” Intravital microscopy in live mice has shown that the elimination of epithelial cells during hair follicle regression involves supra-basal cell...

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Rab32 and Rab38 Crucial for Bone Resorption and Pigmentation of Skin, Hair

Reviewed by Lily Ramsey, LLMOct 26 2023 Bone is maintained via delicate balance between formation and resorption, and its imbalance leads to bone related diseases like osteoporosis rheumatism and periodontitis. In studies published in scientific journals J Biol Chem and Cell Struct Funct, researchers led by Osaka University revealed proteins named Rab32 and Rab38 play...

Eating more fish could reel in heart disease risks, new meta-analysis shows
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Eating more fish could reel in heart disease risks, new meta-analysis shows

By Pooja Toshniwal PahariaOct 30 2023Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in the journal Nutrients, researchers performed a meta-analysis to determine the association between fish consumption and cardiovascular disease (CVD) risk.The Importance of Diet in Cardiovascular Health Studies show that unhealthy dietary habits and sedentary lifestyles contribute to the high mortality...

FDA warns eyedrops from major brands may cause infection
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FDA warns eyedrops from major brands may cause infection

by Cara Murez Federal regulators are warning consumers to stop using eyedrops and gels from several major brands after finding unsanitary conditions in a manufacturing plant. Twenty-six eye care products are part of the alert. Contaminated products have the potential to cause eye infection and blindness because drugs applied to the eye can bypass some...

FDA approves mirikizumab, a promising induction and maintenance therapy for ulcerative colitis
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FDA approves mirikizumab, a promising induction and maintenance therapy for ulcerative colitis

by The Mount Sinai Hospital Endoscopic image of a bowel section known as the sigmoid colon afflicted with ulcerative colitis. The internal surface of the colon is blotchy and broken in places. Credit: Samir/Wikipedia The U.S. Food and Drug Administration (FDA) approved mirikizumab, on October 26, 2023, a highly effective new treatment for ulcerative colitis (UC),...

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Weekly insulin injections could be as effective in diabetes management as daily injection regimes

by University of Surrey Credit: Artem Podrez from Pexels Insulin icodec, a once-weekly basal injection to treat type 1 diabetes, has the potential to be as effective in managing the condition as daily basal insulin treatments, according to research from the University of Surrey. The results of the year-long phase 3 clinical trial could revolutionize the...