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Biosimilar of costly inflammatory bowel disease therapy found safe and effective

Treatment of Crohn’s disease and ulcerative colitis has been greatly improved by the introduction of biologic therapies such as infliximab (which targets tumour necrosis factor alpha), but at considerable cost. A recent analysis of results from 11 published studies including 829 patients shows that a new and lower-cost biosimilar for infliximab—called CT-P13 (Remsima/Inflectra)—has excellent clinical...

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Protein HMGB1 may be the key to better asthma treatment

A new study, published in the Journal of Allergy and Clinical Immunology, investigates a potential new approach to designing drugs for the treatment of asthma. Better interventions could be on the horizon. With asthma cases on the rise, research looking at novel drug targets is more important than ever. Asthma causes an individual’s airways to become inflamed...

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Autoimmune disease: Could modified red blood cells lead to new treatments?

New treatments that prevent and alleviate autoimmune diseases may come from using red blood cells to carry disease-specific proteins that retrain the immune system. So concludes a study that shows such an approach works in mice with multiple sclerosis and type 1 diabetes. The researchers say that their method of using red blood cells to...

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Targeting The Immune System May Help Stop The Itch Of Eczema

A new treatment may help reduce the itch of atopic dermatitis, which will reduce flare-ups. Meredith Rizzo/NPR People with moderate to severe eczema may benefit from new treatments that significantly reduce the intense itching that comes with the scaly skin disease. A study published Wednesday finds that the antibody nemolizumab, given as a monthly injection, not only...

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New eating disorder app helps users by letting them track what they eat and how they FEEL about their food

An app, Recovery Record, has helped bring eating disorder treatment mobile It lets you track what you eat and how you feel about your food The creators say it can help eliminate the shame of face-to-face therapy   The National Eating Disorders Association has partnered with the app to create a new platform that helps users received...

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Could fruit and steak cure epilepsy? Study claims that a low-carb, high-fat diet is the key to controlling seizures as it alters the activity of brain cells

Super-refractory status epilepticus is the most severe classification of epilepsy Figures suggest that the deadly form kills around 60 per cent of all sufferers  But new research shows a ketogenic diet could alleviate symptoms in patients A diet high in fruit and steak could cure a deadly form of epilepsy, scientists have found. Super-refractory status...

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Light-based pain relief goes green

One of the green-lit enclosures used in the study   According to the American Academy of Pain Medicine, approximately 100 million people in the US alone suffer from chronic pain. Although opioids (powerful pain relievers) may help, they can cause serious side effects such as dizziness, vomiting and constipation – plus they’re addictive. So, what...

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Hope for migraine sufferers? Epilepsy drug relieves seizure-like symptoms that cause blinding headaches

Lyrica relieves a seizure-like phenomenon believed to be the cause of migraines It works by stopping a wave of brain cells, preventing symptoms, scientists say And it was found to boost calcium levels, with low amounts causing headaches A drug used to treat epilepsy could end the migraine misery for millions of sufferers, scientists claim....

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Rheumatoid arthritis: New treatment option for difficult-to-treat patients

Between 3 and 5% of the population suffer from a form of inflammatory rheumatism. It affects approximately 250,000 — 400,000 people in Austria. Rheumatoid arthritis is one of the commonest and also the most dangerous forms of this inflammatory rheumatic disease. Around 30% of patients achieve remission, that is to say successful control of symptoms,...