by Indiana University Shotgun metagenomics revealed distinct gut microbiota composition and genetic potential within and between the hyperparasitemia resistant and susceptible mice. a C57BL/6 mice were acquired from four different vendors (N = 15/group): Charles River Laboratories (CR), Envigo (Env), Taconic Biosciences (Tac), and Jackson Laboratory (Jax). Mice from Taconic Biosciences were obtained from two different facilities with...
by Monash University Credit: Pixabay/CC0 Public Domain As little as 1% reduction in deep sleep per year for people over 60 years of age translates into a 27% increased risk of dementia, according to a study which suggests that enhancing or maintaining deep sleep, also known as slow wave sleep, in older years could stave off...
by Baylor College of Medicine Graphical abstract. Credit: Journal of Clinical Investigation (2023). DOI: 10.1172/JCI172503 Improving treatments for triple-negative breast cancer (TNBC), an aggressive tumor with very poor prognosis and limited therapeutic targets, has been challenging. Responding to this need for better treatments, researchers at Baylor College of Medicine and collaborating institutions have investigated potential vulnerabilities...
by University of Birmingham PF4 binding to c-Mpl disrupts TPO binding. (A) AlphaFold prediction of the binding of PF4 and TPO to c-Mpl. Overlayed cartoon structures of c-Mpl (green) complexed with either PF4 (blue) or TPO (orange) as modeled using Colabfold. Structure predictions were ranked by pLDDT, a per-residue measure of the confidence of the predicted...
by Will Cushman, University of Wisconsin-Madison A cancer cell undergoing abnormal mitosis and dividing into three new cells rather than two following treatment with a microtubule poison. Credit: Beth Weaver, University of Wisconsin–Madison A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and...
Dietary measures, medications, and supplements can all help reduce uric acid and manage gout. Gout can occur when blood uric acid levels are too high, causing crystals to form in the feet, toes, and other joints. Uric acid is a chemical the body creates when it breaks down purines. The body creates purines, and some...
Developed by MIT researchers, FibeRobo changes structure with heat and cold. BY ANDREW PAUL | PUBLISHED OCT 26, 2023 4:00 PM EDT This liquid crystal fabric is ‘smart’ enough to adapt to the weather Developed by MIT researchers, FibeRobo changes structure with heat and cold. MIT’s FibeRobo could find its way into jackets, sports bras, and compression garments....
by Ohio State University Medical Center Credit: EKATERINA BOLOVTSOVA from Pexels A new study from The Ohio State University Wexner Medical Center and College of Medicine, University of Utah and University of Exeter (UK) substantiates previous groundbreaking research that rumination (overthinking) can be reduced through an intervention called rumination-focused cognitive behavioral therapy (RF-CBT). In addition, the...
by Tim Tedeschi, University of Cincinnati Credit: Unsplash/CC0 Public Domain A new large-scale study led by researchers at the University of Cincinnati and Northwell Health, New York’s largest health care provider, found the drug metformin can help prevent or reduce weight gain in youth taking medication to treat bipolar disorder. The collaborative team presented its findings...
by Mary Bushell, The Conversation Credit: Unsplash/CC0 Public Domain Stimulants are first-line drugs for children and adults diagnosed with attention-deficit hyperactivity disorder (ADHD). But how do they actually work? First, let’s look at the brain ADHD is a neurodevelopmental condition, which means it affects how the brain functions. Medical imaging indicates people with ADHD may have...
