by deCODE genetics Credit: Pixabay/CC0 Public DomainA large international study led by deCODE Genetics on the genetics of migraine provides novel insights into the biology of migraine enabling detection of rare variants protecting against migraine, opening an avenue for potential development of novel drug targets. In a study published in Nature Genetics a group of...
Author: admin
Key signaling protein identified as possible target for new therapies in hard-to-treat cancers
by American Physiological Society Credit: Function (2023). DOI: 10.1093/function/zqad053The unique signaling protein known as TRPM7 can stimulate and interact with an important cellular signaling hub called the AKT machinery, which is a well-known component of multiple cellular functions that drive growth and proliferation. This interaction causes a significant increase in the gene expression of COX-2, an...
Next-Gen Contact Lenses: Beyond Vision Correction
Dr. Priyom Bose, Ph.D.Reviewed by Danielle Ellis, B.Sc. Contact lenses are ocular prosthetic devices used by millions of people across the world. Although the main application of contact lenses is vision correction, these are also used for cosmetic and medical purposes. The creation of a smart contact lens (SCL) equipped with electronic components, such as...
Student Uses Synthetic Biology to Create Low-Cost Diagnostic Tools
Posted Today New application of synthetic biology: Justin Vigar, pictured here in a lab in South America, is developing paper-based diagnostics like the paper chip shown on the right, where each dot represents a different test. Image credit: University of Toronto Justin Vigar and his colleagues are creating a customizable, paper-based platform to rapidly screen for...
New method tracks how brain cells age
Peer-Reviewed Publication ROCKEFELLER UNIVERSITY Hospital nurseries routinely place soft bands around the tiny wrists of newborns that hold important identifying information such as name, sex, mother, and birth date. Researchers at Rockefeller University are taking the same approach with newborn brain cells—but these neonates will keep their ID tags for life, so that scientists can...
New nano particles found to be effective for the treatment of rheumatoid arthritis
Ceria nano particle-immobilized mesenchymal stem cell nanovesicle hybrid system offers both immediate pain relief and long-term immune tolerance Peer-Reviewed Publication INSTITUTE FOR BASIC SCIENCE SCHEMATIC ILLUSTRATION OF COMPREHENSIVE AND COMBINATION RA THERAPY BY CE-MSCNV NANOPARTICLES. CE-MSCNVS SCAVENGE THE OVER-PRODUCED ROS IN AN RA KNEE JOINT, INDUCE M1 TO M2 MACROPHAGE POLARIZATION FOR IMMEDIATE RELIEF OF...
Psoriasis not caused by spontaneous mutations in skin cells
Genetic analysis of psoriasis shows somatic mutations are not linked to the development or the spread of the condition.Peer-Reviewed Publication WELLCOME TRUST SANGER INSTITUTE Psoriasis — a chronic skin condition — is not caused or spread by spontaneous genetic mutations in the skin, new research suggests. The team, from the Wellcome Sanger Institute and collaborators,...
Researchers identify amino acid that may play a key role for predicting and treating long COVID
Phase 3 trial of supplement proposed, new diagnostic tool to be validated.Peer-Reviewed Publication UNIVERSITY OF ALBERTA University of Alberta researchers have identified an amino acid that may play a key role in predicting poor clinical outcomes and the treatment of long COVID. In research published today in Cell Reports Medicine, the team says it has...
Breast cancer survivors: New training to treat ‘chemo-brain’
by University of Reading Credit: Pixabay/CC0 Public DomainA form of computerized attention and memory training can improve impaired attention and memory issues in women treated for breast cancer, University of Reading researchers have found. “Chemo-brain” refers to cognitive problems like forgetfulness, difficulty concentrating, and lapses in everyday attention, which are common side effects of breast cancer...
Treating amphetamine use disorder with stimulants: An encouraging new approach
by Society for the Study of Addiction Credit: Unsplash/CC0 Public DomainA new study has found that it may be possible to use stimulants to treat stimulant use disorder. People with amphetamine-type stimulant use disorder who are treated with prescription psychostimulants such as methylphenidate and dextroamphetamine (commonly used to treat attention deficit hyperactivity disorder (ADHD)) may...