RADIOLOGICAL SOCIETY OF NORTH AMERICA IMAGE: BRAIN MRI OF A 72-YEAR-OLD WOMAN SHOWS LOSS OF VOLUME OF THE HIPPOCAMPUS (ARROWS). THE PATIENT HAD ALL THREE CHARACTERISTICS, VOLUME LOSS OF THE HIPPOCAMPI, APOE4, AND ANXIETY, FOUND IN THESTUDY TO BE ASSOCIATED WITH PROGRESSION FROM MILD COGNITIVE IMPAIRMENT TO DEMENTIA. OAK BROOK, Ill. – Anxiety is associated...
by Alice McCarthy, Children’s Hospital Boston PET scan of a human brain with Alzheimer’s disease. Research into Alzheimer’s disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients’ brain tissue, a pathological form of the tau protein contributes to propagating the disease in the...
By Nick Lavars, November 15, 2020 A new study has highlighted the role gut bacteria may play in Alzheimer’s disease, while inflammation may also have a part to play Research into the relationship between the brain and the bacteria in our bellies is uncovering links to an increasing number of neurological conditions, with Alzheimer’s among them....
A fringe theory links microbes in the brain with the onset of dementia. Now, researchers are taking it seriously. Alison Abbott Some scientists think that microbes such as the herpes simplex virus 1 (shown here on an epithelial cell) could trigger some cases of Alzheimer’s disease. Two years ago, immunologist and medical-publishing entrepreneur Leslie Norins offered to...
Multi-lab research program analyzes cerebrospinal fluid molecules to seek diagnostic and progression markers as well as treatment targets. A major scientific effort is underway to characterize the proteins in the cerebrospinal fluid to improve diagnostics and clinical monitoring assays and discover potential therapies, for Alzheimer’s disease. Several research labs at the University of Washington School of Medicine and Stanford...
UNIVERSITY OF SOUTH FLORIDA (USF HEALTH) IMAGE: UNIVERSITY OF SOUTH FLORIDA HEALTH NEUROSCIENTIST CHUANHAI CAO, PHD, LED THE PRECLINICAL STUDY TESTING A NOVEL THERAPEUTIC ALZHEIMER’S VACCINE. TAMPA, Fla (Oct. 20, 2020) — Our immune system’s capacity to mount a well-regulated defense against foreign substances, including toxins, weakens with age and makes vaccines less effective in...
by University of Pittsburgh Associate professor of epidemiology, University of Pittsburgh Graduate School of Public Health. A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia—with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health. Their study,...
TOKYO METROPOLITAN UNIVERSITY IMAGE: THE MUTANT MARK4 CREATES A FORM OF TAU WHICH ACCUMULATES EASILY IN BRAIN CELLS, CAUSING NEURONS TO DIE. Tokyo, Japan – Researchers from Tokyo Metropolitan University have discovered a new mechanism by which clumps of tau protein are created in the brain, killing brain cells and causing Alzheimer’s disease. A specific mutation to...
by Delthia Ricks , Medical Xpress Binge drinking may be linked to both the onset and severity of Alzheimer’s disease, but scientists have only now embarked on a path to decipher each molecular step involved in how excessive alcohol consumption leads to the most common form of dementia. The research, underway at the Feinstein Institutes for...
UNIVERSITY OF SOUTHERN CALIFORNIA A new Alzheimer’s study found that impaired blood flow in the brain is correlated with the buildup of tau tangles, a hallmark indicator of cognitive decline. The work, published this week in the Journal of Neuroscience, suggests that treatments targeting vascular health in the brain — as well as amyloid plaques and tau...
