UNIVERSITY OF EASTERN FINLAND A new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer’s disease, enhances several key functions of immune cells. The results obtained in the study highlight the importance of immune cells as a target of future development of new therapies for Alzheimer’s...
Category: <span>Alzheimer’s</span>
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new alteration in the brain of people with Alzheimer’s discovered
SPANISH NATIONAL RESEARCH COUNCIL (CSIC) Despite the important advances in research in recent years, the etiopathogenesis of Alzheimer’s disease is still not fully clarified. One of the key questions is to decipher why the production of beta amyloid, the protein that produces the toxic effect and triggers the pathology, increases in the brain of people...
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Keto diet may reduce Alzheimer’s risk by altering gut fungi
Scientists have found associations between fungi living in the gut and mild cognitive impairment, which can lead to Alzheimer’s disease. They suggest that a ketogenic diet could help prevent the disease by creating a more healthful balance of microorganisms in the gut. SA ketogenic diet may help cut the risk of Alzheimer’s by influencing the...
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MSK study links inflammation to Alzheimer’s disease development
MEMORIAL SLOAN KETTERING CANCER CENTER Alzheimer’s disease is a neurodegenerative condition that is characterized by the buildup of clumps of beta-amyloid protein in the brain. Exactly what causes these clumps, known as plaques, and what role they play in disease progression is an active area of research important for developing prevention and treatment strategies. Recent...
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Gene therapy could potentially reverse memory loss from Alzheimer’s in humans
Researchers from Macquarie University have discovered a world-first new treatment that reverses the effects of memory loss associated with Alzheimer’s disease in a study of mice with advanced dementia. The research, co-led by two brothers, Dr Arne Ittner and Professor Lars Ittner, from Macquarie University Dementia Research Centre, builds on their work begun in 2016...
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Female chromosomes offer resilience to Alzheimer’s
by University of California, San Francisco Women with Alzheimer’s live longer than men with the disease, and scientists at UC San Francisco now have evidence from research in both humans and mice that this is because they have genetic protection from the ravages of the disease. By virtue of having a second X chromosome, women...
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Diabetes medication could help reducing one of the worst effects of aging
Aging is just not fun. At the later stages of your life you are more likely to encounter some serious health problems, such as Alzheimer’s disease. Once you hear this diagnosis, you know you’re in for a bad ending, because it is incurable. However, now scientists at the University of Toronto and the Sunnybrook Research...
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New molecule reverses Alzheimer’s-like memory decline
by Salk Institute A drug candidate developed by Salk researchers, and previously shown to slow aging in brain cells, successfully reversed memory loss in a mouse model of inherited Alzheimer’s disease. The new research, published online in July 2020 in the journal Redox Biology, also revealed that the drug, CMS121, works by changing how brain...
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Study in mice finds potential therapy to reverse memory loss from Alzheimer’s
by Macquarie University Researchers from Macquarie University have discovered a world-first new treatment that reverses the effects of memory loss associated with Alzheimer’s disease in a study of mice with advanced dementia. The research, co-led by two brothers, Dr. Arne Ittner and Professor Lars Ittner, from Macquarie University Dementia Research Center, builds on their work...
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AsEH enzyme: A new pharmacological target against Alzheimer’s disease
Drugs with neuroprotector effects UNIVERSITY OF BARCELONA FROM LEFT TO RIGHT, SANTIAGO VÁZQUEZ, CARLES GALDEANO, MERCÈ PALLÀS AND CHRISTIAN GRIÑÁN-FERRÉ (FACULTY OF PHARMACY AND FOOD SCIENCES/UNIVERSITY OF BARCELONA)…. view more CREDIT: UNIVERSITY OF BARCELONA A UB study published in the journal Neurotherapeutics has validated a new pharmacological target for Alzheimer’s disease. The results show the...