by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a possible treatment for Alzheimer’s disease. Working together with a scientific team at the Rockefeller University in New York, the investigators have shown that treatment with the oral anticoagulant dabigatran delays the appearance of Alzheimer’s disease in mice. The results published today in the Journal of the American College...
Category: <span>Alzheimer’s</span>
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Chemist discovers promising compound for a future drug against Alzheimer’s disease
by RUDN University Biochemists from RUDN University (Russia) and the University of Bari (Italy) report a group of compounds that can become a molecular scaffold for new drugs for Alzheimer’s disease. They have demonstrated that derivatives of 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole, or HHAI, are effective inhibitors of acetylcholinesterase and butyrylcholinesterase—enzymes whose increased activity can worsen the condition in...
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Tracking Alzheimer’s disease pathology in single neuronal cells
UNIVERSITY OF WARWICK Aggregates of Tau protein in the brain are a hallmark of neurodegeneration, particularly in Alzheimer’s disease. Researchers at the University of Warwick have introduced fluorescently labelled Tau aggregates (oligomers) into single brain neurons and were able to track their movement and effects. They found the introduced Tau oligomers interfered with the action potential waveform, modified the...
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Is copper a cause of Alzheimer’s disease?
University of Houston researcher examines the link UNIVERSITY OF HOUSTON A University of Houston chemist is exploring the link between copper protein molecules in brain cells and neurodegenerative diseases like Alzheimer’s. “Scientists have studied Alzheimer’s disease for 100 years and still no one knows the cause,” said assistant professor of chemistry Tai-Yen Chen, who will...
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Alzheimer’s research increasingly focused on links to sleep and other behaviors
by Elsevier Sleep and other behavioral topics are growing within Alzheimer’s disease research, according to a new report released today by Elsevier, a global information analytics business specializing in science and health. To coincide with World Alzheimer’s Month, Elsevier analyzed Alzheimer’s research published since the 1970s offering a comprehensive view of the landscape of Alzheimer’s...
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Scientists link ‘hunger hormone’ to memory in Alzheimer’s study
UNIVERSITY OF TEXAS AT DALLAS Scientists at The University of Texas at Dallas have found evidence suggesting that resistance to the “hunger hormone” ghrelin in the brain is linked to the cognitive impairments and memory loss associated with Alzheimer’s disease (AD). The findings, based on observations of postmortem brain-tissue samples from Alzheimer’s patients and on experiments with a mouse model of AD, also...
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Eye-tracking tests may be key to predicting who will develop Alzheimer’s disease, study finds
by Loughborough University New research has found that it may be possible to predict if people with mild memory and thinking impairments will go onto develop Alzheimer’s disease using eye-tracking technology. Dr. Thom Wilcockson, of Loughborough University’s School of Sports, Exercise and Health Sciences, says he hopes the findings in the new paper he is...
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When Technology Remembers: Digital Health And Alzheimer’s Disease
The Medical Futurist Gradual memory loss, cognitive decline, wandering off to unknown places, being unable to dress in the morning: to live with dementia and Alzheimer’s disease might be a heart-wrenching burden for both patients and their loved ones. As the global population ages, and the number of individuals suffering from these conditions rises, digital...
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Study eyes role of Apple smart devices to help identify early stage AD
by Nancy Cohen , Medical Xpress A study conducted by Evidation Health on behalf of Eli Lilly and Apple suggests that data collected from smart devices and digital apps might help speed up the diagnosis of early stages of Alzheimer’s disease. The study, “Developing Measures of Cognitive Impairment in the Real World from Consumer-Grade Multimodal...
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Transcranial Electromagnetic Treatment Halts, Reverses Alzheimer’s
MEDGADGET EDITORSMEDICINE, NEUROLOGY, NEUROSURGERY, REHAB The MemorEM system from NeuroEM Therapeutics, a company based in Phoenix, Arizona, delivers transcranial electromagnetic treatment, or TEMT, to the brains of patients in two one-hour sessions each day for two months. This involves propagating electromagnetic waves toward β-amyloid aggregates that seem to be responsible for the symptoms of Alzheimer’s....