MOSCOW INSTITUTE OF PHYSICS AND TECHNOLOGY A joint research team from Russia and the U.K. has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs, or “plastic antibodies.” NanoMIPs are synthetic polymers that can function as antibodies, selectively binding to target proteins on the surface of cancer cells. This approach could lead...
Category: <span>Cancer</span>
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Compound discovered that targets cancer cells lacking the protective p53 ‘guardian gene’
Developed and tested at the University of Huddersfield, the compound, containing ruthenium, is attracted to the vulnerable cancer cells, whilst leaving healthy cells untouched UNIVERSITY OF HUDDERSFIELD A NEW chemical compound with the potential to destroy hard-to-treat cancer cells has been developed and tested by scientists at the University of Huddersfield. Also, the compound causes...
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NUS study: RUNX proteins act as regulators in DNA repair
Findings open opportunities to target RUNX-deficient cancers such as breast cancer and leukemia NATIONAL UNIVERSITY OF SINGAPORE A study by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has revealed that RUNX proteins are integral to efficient DNA repair via the Fanconi Anemia (FA) pathway. IMAGE: A RESEARCH TEAM FROM THE CANCER...
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To find and disarm: Scientists develop platform to kill cancer cells
NATIONAL UNIVERSITY OF SCIENCE AND TECHNOLOGY MISIS The new treatment will serve as both diagnosis and treatment of malignant tumors. This breakthrough in the technologies of cancer diagnosis and treatment was made by an interdisciplinary Russian-German collaboration of chemists, physicists, and biologists from NUST MISIS, Lomonosov Moscow State University, Pirogov Russian National Research Medical University (RNRMU), and...
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Electric fields: cancer killers?
Pulsing cells with electric fields can force calcium diffusion into cells. Researchers have now optimized this technique in an attempt to kill cancer cells and leave healthy cells intact. Researchers from the Bioelectrics Department of Kumamoto University (Japan) have identified the optimal pulsed electric field (PEF) conditions for the maximum calcium cell membrane permeability. There...
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Scientists identify genetic marker for gastric cancer prognosis
Although immunotherapy is seen as a very promising treatment for cancer, currently only 20 to 30 percent of patients respond positively. Being able to identify the people most likely to benefit from the costly therapy is a Holy Grail for oncologists. Histopathology of Helicobacter pylori infection in a gastric foveolar pit demonstrated in endoscopic gastric...
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Kidney cancer’s developmental source revealed
In the first experiment of its kind, scientists have revealed the precise identity of cancer cells of the most common childhood and adult kidney cancers. Researchers from the Wellcome Sanger Institute, the University of Cambridge, University of Newcastle and their collaborators showed that the cancer cells are versions of specific healthy cells from developing or adult kidneys....
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New finding could ‘pause and rewind’ lung cancer
A team of Institute researchers has discovered how to stop and reverse the growth of lung cancer with a potent combination of three molecules. Lung CA seen on CXR. Credit: James Heilman, MD/Wikipedia The study found that two BH3-mimetics and one FGFR inhibitor were able to block lung cancer cell survival so successfully in pre-clinical models that tumors not...
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Cancer cells are weaker when made more acidic
Cancer cells function less well and are less able to multiply when their internal environment is made more acidic. Making cancer cells more acidic could quell their ability to multiply. This was the conclusion that researchers in the United States and Spain came to after they used a computer model to study the conditions that affect metabolic...
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Scientists develop novel drug that could potentially treat liver cancer more effectively
A research team led by scientists from the Cancer Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has developed a novel peptide drug called FFW that could potentially stop the development of hepatocellular carcinoma (HCC), or primary liver cancer. This landmark discovery opens the door for more effective treatment of liver cancer with...