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Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer
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Real-world data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer

by Perelman School of Medicine at the University of Pennsylvania Credit: Pixabay/CC0 Public Domain Over the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment for patients with advanced lung cancer, helping many live longer lives and improving overall survival for the disease. However, an important question has remained unanswered: How long should a...

Magnetic microrobots with folate targeting for drug delivery
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Magnetic microrobots with folate targeting for drug delivery

BEIJING INSTITUTE OF TECHNOLOGY PRESS CO., LTD  IMAGE: THE INTRODUCTION OF FA IMPROVED THE TUMOR TARGETING ABILITY OF THE MICROROBOTS, WHICH CAN BE MANIPULATED BY MAGNETIC FIELDS, PRODUCING AN OBVIOUS ANTICANCER EFFECT. CREDIT: CYBORG AND BIONIC SYSTEMS The limited ability of microrobots to assist drugs in entering cells hinders their therapeutic efficacy. To address this,...

Treatment found to reduce progression of rare blood cancer by 74%
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Treatment found to reduce progression of rare blood cancer by 74%

Credit: Wikimedia Commons A treatment that involves genetically modifying the body’s own immune cells has been found to cut the risk of disease progression by 74 percent in people with a rare type of blood cancer, results showed Monday. Ciltacabtagene autoleucel—also known by its trade name Carvykti—was tested in a clinical trial involving 419 patients with multiple...

How the combination of advanced ultrasound and AI could upgrade cancer diagnostics
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How the combination of advanced ultrasound and AI could upgrade cancer diagnostics

by National Institutes of Health A new imaging technique that combines cutting-edge ultrasound technology with AI can tell whether a thyroid tumor is malignant or not by peering into its microvasulature — a capability that has been out of reach with conventional ultrasound alone. Credit: Dr. Azra Alizad and Dr. Mostafa Fatemi’s research team.  National Institutes of Health Researchers have...

For advanced, HER2-amplified bile duct cancers, antibody treatment trial shows promising results
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For advanced, HER2-amplified bile duct cancers, antibody treatment trial shows promising results

by Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering gastrointestinal oncologist Dr. James Harding. Credit: Memorial Sloan Kettering Cancer Center Bile duct cancers are uncommon and aggressive types of gastrointestinal cancer. They include cholangiocarcinomas, which can form inside or outside of the liver, as well as cancers of the gallbladder, and are highly likely to cause...

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Nature-inspired compounds chop up cancer gene’s RNA

Resarchers have found new possibilities for targeting cancer genes’ RNA with nature-inspired compounds. The cancer gene MYC drives the unrestrained growth of most human cancers. It has been called the “Mount Everest” of oncological research because of the difficulty of designing medications that can disable it, and the expectation that an effective MYC drug could help so...

Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response
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Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response

by Baylor College of Medicine Credit: Unsplash/CC0 Public Domain Researchers at Baylor College of Medicine have discovered a crucial regulator of the anti-cancer immune response that could change the game in the fight against cancer. Published in the Proceedings of the National Academy of Sciences, the study shows that in animal models of breast and prostate cancer, eliminating...

Major progress in curing brain tumors by blocking certain functions in cells with a docked molecule
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Major progress in curing brain tumors by blocking certain functions in cells with a docked molecule

by University of Gothenburg The researchers’ molecule Z4P inhibits one of the mechanisms that regulate protein production in a cancer cell. This inhibition causes the cancer cell to die. Three pictures show the spread of the tumor after 20 days of treatment on mice. Control: Untreated tumor. TMZ: Follow-up treatment solely with chemotherapy. Combo: Combination treatment with...

Intratumoral Bacteria as an Injectable Anti-Cancer Treatment
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Intratumoral Bacteria as an Injectable Anti-Cancer Treatment

MAY 19TH, 2023 CONN HASTINGS  MEDICINE, ONCOLOGY Scientists at the Japan Advanced Institute of Science and Technology in Ishikawa, Japan have developed an anti-cancer treatment that consists of bacteria that are naturally found inside some tumors. Isolating and then injecting these bacteria into existing tumors appears to provoke a strong immune response that can lead to...

Researchers find link between obesity and blood cancer
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Researchers find link between obesity and blood cancer

by Jackie Maupin, Indiana University School of Medicine Credit: Unsplash/CC0 Public Domain Indiana University School of Medicine researchers studying clonal hematopoiesis of indeterminate potential (CHIP), a blood condition that may increase the risk of blood cancer, discovered that obesity was strongly associated with the condition. Their findings were recently published in the Journal of Clinical Investigation. CHIP...