Topsalysin is injected into tumours but leaves surrounding tissue and intact Drug is currently being trialled by doctors and is being hailed as breakthrough Doctors say drug could help thousands of men without the risk of side effects Prostate cancer is most common cancer in men, with more than 46,000 diagnosed in the UK each year A...
Category: <span>Cancer</span>
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Partnering cells turn off immune attack on pancreatic tumors
Two cell types work together to protect pancreatic tumors from destruction by the immune system. But, blocking this partnership may restore the system’s ability to attack these same tumor cells. These are the findings of a study in mice led by researchers from NYU Langone Medical Center and its Perlmutter Cancer Center, and published online...
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New way found to boost immunity in fight cancer and infections
An international research team led by Université de Montréal medical professor Christopher Rudd, director of research in immunology and cell therapy at Maisonneuve-Rosemont Hospital Research Centre, has identified a key new mechanism that regulates the ability of T-cells of the immune system to react against foreign antigens and cancer. T-cells orchestrate the response of the...
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Hormone replacement therapies help breast cancer grow, spread
Hormone replacement therapies could cause specialized cancer cells to induce growth, metastasis Hormone replacement therapies, or medications containing female hormones that substitute those no longer produced by the body, often are prescribed to reduce the effects of menopausal symptoms in women. Research has indicated that women who take hormone replacement therapies have a higher incidence...
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Researchers engineer macrophages to engulf cancer cells in solid tumors
One reason cancer is so difficult to treat is that it avoids detection by the body. Agents of the immune system are constantly checking the surfaces of cells for chemical signals that say they belong, but cancer cells express the same chemical signals as healthy ones. Without a way for the immune system to tell...
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Cancer may metastasize without lymph node involvement
NFCR-funded research finds two distinct patterns of metastatic spread in human colorectal cancer (Bethesda, MD, July 13, 2017) Research by several leading scientists including Rakesh Jain, PhD, Director of the Edwin L. Steele Laboratory for Tumor Biology at the Massachusetts General Hospital and supported in part by the National Foundation for Cancer Research, has provided...
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Immunosuppression Underlies Resistance to Anti-angiogenic Therapy
A Massachusetts General Hospital (MGH) research team has identified a novel mechanism behind resistance to angiogenesis inhibitors – drugs that fight cancer by suppressing the formation of new blood vessels. In their report published in the Journal of Clinical Investigation, the team based in the Edwin L. Steele Laboratories for Tumor Biology in the MGH Department of Radiation Oncology describes...
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Could the FLU cure cancer? Injecting inoperable patients with the common virus destroys their tumours and could be a ‘game-changing’ new treatment
Scientists are to trial the new treatment on humans with advanced liver cancer Initial tests have already shown the strange technique to shatter tumours in mice Volunteers will all have a runny nose after being given the jab, doctors suspect The common cold virus could have the power to destroy tumours in cancer patients, scientists suspect. Doctors...
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CNIC scientists find the key to improved cancer immunotherapy
The study, published in Nature Communications, demonstrates that tissue-resident and circulating memory T cells cooperate in anti-tumor immunity Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) have investigated how different subtypes of essential immune-response cells called CD8+ T lymphocytes cooperate to mount a stronger anti-tumor response. The results show that generation of...
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Using Light to Activate Genes and Kill Cancer
Scientists at Kyoto University in Japan have developed a gene delivery system, involving gold nanorods and a near infrared laser, which can transport a gene into cells and activate it. Changing gene expression is a powerful way to affect cell behavior, and scientists hope to use this approach to treat a variety of diseases. Researchers...