A brand new personalized cancer vaccine has been designed to target 20 mutated proteins unique to each patient’s tumors. The vaccine seems to have prevented early relapses in 12 patients with skin cancer, making them cancer free for more than 2 years A therapy for each patient: There are many different forms of Cancer and...
Category: <span>Cancer</span>
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A potential cure for Metastatic prostate cancer
All forms of metastatic prostate cancer have been considered incurable in the past. However, in the recent years, FDA has approved 6 drugs for men with metastatic disease, all of these can increase survival. In a study published in Urology, researchers demonstrate for the 1st time that a combination of systemic therapy (Drug therapy) +...
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CRISPR cousin SHERLOCK may be able to track down diseases
CRISPR is known as the genome-editing power house so far. Recently scientists have discovered a far more superior diagnostic tool known as SHERLOCK. That achievement described in Science, would pave way for quick, easy, cheap and precise diagnostic tests. Researchers have developed a promising method for detecting extremely low concentrations of genetic material. Though there...
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Are tumor cells Glutamine addicts?
Most cancers require large amounts of glutamine for rapid growth and there are numerous studies indicating that they cannot survive without it, a phenomenon termed ad “glutamine addiction”. This led to the idea that preventing tumors from glutamine uptake could be a potential therapeutic strategy. Researchers from Berlin and Wurzburg, Germany conclude that glutamine deprivation...
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Specialized blood vessels enhance tumor-fighting Immunotherapy
Researchers from VIB and KU Leuven, together with colleagues from the University of California and the Swiss Institute for Experimental Cancer Research have demonstrated that, anti-angiogenic therapy can improve immune boosting treatments. The combination of these two therapies result in the growth of specialized vessels that deliver cancer-fighting immune cells to the tumor, potentially leading...
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Immune system could identify changes in cancer antigen
A new study has identified novel mechanisms where T cells may be able to differentiate an emerging class of targets specifically increased on Cancer cells. Researchers from the University of Virginia and Brimingham have published their study in Oncotarget, focuses on how immune system recognizes protein targets that are modified by phosphorylation- it is known...
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Defeating cancer using Gene regulation
Scientists are finding ways to put on and off genes as a means of battling cancer, which would eventually lead to highly personalized treatment for cancer at the genetic level. Such methods could shut down cancer’s defenses against medications. The code treatment; The molecular insight into our own DNA is now possible through a field...
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Th17 cells could facilitate wider clinical use of adoptive Immunotherapy
Researchers at Medical University of South Carolina (MUSC) report that long-term expansion protocols for adoptive cancer immunotherapy does not compromise Th17 cells’ effectiveness against large tumors in the March 9.2017 issue of JCI insight. This is a significant finding because rapid expansion protocols (REPs) that are used to produce sufficient CD8+ T cell numbers for...
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Team examines use of anti-parasitic drug as new treatment for brain tumors
Marc Symons, PhD, professor in The Feinstein Institute for Medical Research’s Karches Center for Oncology Research, is examining if a common medication administered to treat pinworms, could replace the current treatment used for certain brain cancers. These findings, which are published today in the Feinstein Institute Press’s peer-reviewed, open-access journal Molecular Medicine, could help to...
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Researchers find novel way to induce pancreatic cancer cell death
Pancreatic cancer: Pancreatic cancer, most frequently pancreatic ductal adenocarcinoma (PDAC), is the most lethal and aggressive of all cancers. Unfortunately, there are not many effective therapies available other than surgery, and that is not an option for many patients. scientists at Wake Forest Baptist Medical Center in collaboration with those at the University of Texas...