A new study that confirms the role of a protein called PAK4 in the movement and growth of pancreatic cancer cells could help researchers find new ways to tackle the disease. The work, funded by national charity Pancreatic Cancer Research Fund, uncovers new evidence that PAK4 plays a key role in enabling cancer cells to...
Category: <span>Cancer</span>
Post
Organo-metal compound seen killing cancer cells from inside
Cancer cells seen to be targeted and killed from the inside with metal-based compound discovered by the University of Warwick The compound – Organo-Osmium FY26 – attacks the weakest part of cancer cells. FY26 is 50x more active than metal drugs used in current cancer treatments Unprecedented minute detail of cancer cells seen with nano-imaging...
Post
How cancers trick the immune system into helping rather than harming them
Scientists at Trinity College Dublin have discovered how certain cancers hijack the immune system for their benefit — tricking it into helping rather than harming them. While most of us are aware that our immune system protects us from infection, we may be less aware of the key role that cells of the immune system also...
Post
Study unveils new way to starve tumors to death
Blocking cancer cells’ metabolism may make treatments more effective, less toxic Unlike a healthy cell, a sarcoma cell (above) relies on environmental sources of arginine, an important protein building block. Remove environmental arginine and the cell must begin a process called autophagy, or ‘self-eating,’ to survive. A second hit to its survival pathways then kills...
Post
Researchers Turn To Artificial Intelligence To Reach New, Previously Unachievable Cancer Outcomes
Artificial intelligence (AI) has been used to gain understanding into the biophysics of cancer. A machine learning platform predicted a trio of reagents capable of generating a one-of-a-kind cancer-like phenotype in tadpoles. The study, conducted by researchers at Tufts University’s School of Arts and Sciences, the Allen Discovery Center at Tufts, and the University of Maryland,...
Post
UNRAVELING THE MYSTERY OF WHY CANCER CELLS SURVIVE AND THRIVE
Some cancer cells have a trick up their sleeve to avoid cell death: boosting maintenance of telomeres, the protective “end caps” on chromosomes, a research team led by Jackson Laboratory (JAX) Professor Roel Verhaak reports in Nature Genetics. The findings open avenues for functional studies that may yield insight into how to steer cancer cells away from immortalizing...
Post
Diabetes or its rapid deterioration can be an early warning sign for pancreatic cancer
Patients and their doctors should be aware that the onset of diabetes, or a rapid deterioration in existing diabetes that requires more aggressive treatment, could be a sign of early, hidden pancreatic cancer, according to research presented at the European Cancer Congress 2017 today (Monday). Ms Alice Koechlin, from the International Prevention Research Institute in...
Post
Mesothelioma shows promising response to existing immunotherapy drug
An existing immunotherapy drug called pembrolizumab appears to be effective in the treatment of malignant pleural mesothelioma, a rare and aggressive lung cancer that is primarily caused by exposure to asbestos. Writing in The Lancet Oncology, researchers describe the first study to show a positive result from using the antibody drug against this rare cancer. Researchers...