Josep Carreras Leukaemia Research Institute image: The Chromatin biology laboratory, led by Dr. Alejandro Vaquero, from the Josep Carreras Leukaemia Research Institute Credit: Josep Carreras Leukaemia Research Institute Over four hundred people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic Leukaemia (B-ALL) next year in Spain, according...
Category: <span>Cancer</span>
Post
Next-gen cell-penetrating antibodies for tumor targeting and RAD51 inhibition
“Overall, the data presented in this study affirm that humanizing 3E10 preserves its crucial biological properties essential for therapeutic efficacy.” Impact Journals LLC image: Figure 1: 3E10 humanization and heavy and light chain variant screening. (A) Diagram of the 3E10 antibody engineering process. The original murine wild-type 3E10 was modified to contain a human IgG1 Fc...
Post
How cancer cells may be using ribosomes to hide from the immune system
A ribosome, its different parts depicted in different colors. Ribosomes are the protein factories of our body’s cells. Credit: Netherlands Cancer Institute The protein factories of our cells are much more diverse than we thought they were. Scientists from the Netherlands Cancer Institute have now shown that cancer cells can use these ribosomes to boost...
Post
Colorectal cancer diagnosis found to impact lives of younger adults differently than older adults
Credit: Andrea Piacquadio from Pexels Younger adults with colon cancer tend to be diagnosed at a later stage and have more aggressive types of tumors. Additionally, young patients living with colorectal cancer have long-term, adverse consequences on their lives, which are different from the impact the disease has on older adults, according to two studies...
Post
Researchers identify new therapeutic approach to preventing cancer from spreading to the brain
October 1, 2024 by McMaster University In a study published in the journal Cell Reports Medicine, researchers Sheila Singh and Jakob Magolan discovered a critical vulnerability in metastatic brain cancer, which they say can be exploited with new drugs to prevent spread. Singh, a professor in McMaster’s Department of Surgery and director of the Center...
Post
Breast cancer drug shows potential for rare appendix cancer
As an NCI-designated Comprehensive Cancer Center, Moores Cancer Center at UC San Diego Health is among the top 4% of approximately 1,500 cancer centers in the United States, and one of only 57 Comprehensive Cancer Centers in the nation. Credit: Kyle Dykes, UC San Diego Health Researchers at University of California San Diego School of...
Post
Bacterial vaccine shows promise as cancer immunotherapy
Columbia researchers have engineered bacteria as personalized cancer vaccines that activate the immune system to specifically seek out and destroy cancer cells. Columbia University Irving Medical Center image: Engineered bacterial cells (purple) activate several parts of the immune system to attack tumor cells (gray). Credit: Columbia University Columbia researchers have engineered probiotic bacteria that educate...
Post
Researchers evaluate beneficial effects of fermented black garlic extract on prostate cancer
Effects of aged black garlic water extract (ABGE) on cell proliferation of control prostate (PNT-2) (a), androgen-dependent (LNCaP) (b), and androgen-independent (PC-3) (c) prostate cancer (PCa) cells. Cell proliferation and growth were evaluated by resazurin reagent after incubation for 24, 48, and 72 h of PNT-2, LNCaP, and PC-3 cell lines with ABGE at different...
Post
Study suggests around 40% of postmenopausal hormone positive breast cancers are linked to excess body fat
Credit: Bryce Carithers from Pexels Around 40% of postmenopausal hormone positive breast cancer cases may be linked to excess body fat, suggests Spanish research published online in the Journal of Epidemiology & Community Health. This proportion is significantly higher than one in 10 such cases currently attributed to excess weight, using the widely used measure of...
Post
In beer yeast, scientists find potential path to starving cancer
University of Virginia Health System image: The unexpected findings could lead to new strategies for making cancer cells more vulnerable to starvation and easier to treat, said researcher Ahmad Jomaa, PhD, of the University of Virginia School of Medicine’s Department of Molecular Physiology and Biological Physics. Credit: Courtesy Jomaa lab The discovery of a surprising...