Since the 1950s, a chemotherapy drug known as 5-fluorouracil has been used to treat many types of cancer, including blood cancers and cancers of the digestive tract. Doctors have long believed that this drug works by damaging the building blocks of DNA. However, a new study from MIT has found that in cancers of the...
Category: <span>Cancer</span>
Post
Uterine cancer rates are increasing: What can you do to protect yourself?
Uterine cancer is the most common type of gynecologic cancer. It’s estimated that about 67,880 new cases will be diagnosed in 2024. Approximately 13,250 people will die from this disease in the U.S. in 2024, according to the National Cancer Institute. Researchers recently reported that while death rates for the most common type of uterine cancer—endometrioid cancer—remained stable, deaths from...
Post
Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma
Credit: Pixabay/CC0 Public Domain In the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T therapy for multiple myeloma, patients experienced efficacy and safety results similar to those seen in clinical trials, according to results published in Blood. Of 236 patients who received cilta-cel infusions at 16 U.S. medical centers in 2022,...
Post
New imaging technique accurately detects aggressive kidney cancer
Representative imaging with [89Zr]Zr-girentuximab. Credit: The Lancet Oncology (2024). DOI: 10.1016/S1470-2045(24)00402-9 A new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form of kidney cancer. The findings, published in The Lancet Oncology, could greatly reduce the number...
Post
In situ tumor vaccine with optimized nanoadjuvants and lymph node targeting capacity to treat ovarian cancer and metastases
News Release 25-Sep-2024 Peer-Reviewed PublicationCompuscript Ltd This new article publication from Acta Pharmaceutica Sinica B, discusses the use of in situ tumor vaccine with optimized nanoadjuvants and lymph node targeting capacity to treat ovarian cancer and metastases. Tumor vaccine, a promising modality of tumor immunotherapy, needs to go through the process of tumor antigen generation...
Post
Clinical trial results show low-intensity therapy can achieve positive outcomes for certain pediatric leukemia subtypes
September 24, 2024 by St. Jude Children’s Research Hospital Clinical trial results from St. Jude Children’s Research Hospital demonstrate the benefits of using genomics and early treatment response to guide risk classification of children with B-cell acute lymphoblastic leukemia (B-ALL). Traditionally, the intensity of a patient’s chemotherapy regime is guided by the National Cancer Institute...
Post
Scientists uncover limits of metabolic flexibility in squamous cell skin cancer
September 23, 2024 by Ani Vahradyan, University of California, Los Angeles Microscopy image of a squamous cell carcinoma, stained with glutamine transporter (ASCT2, green) and nuclei (DAPI, blue). This tumor lacks the enzyme LDHA, which normally helps cells process glucose. Credit: William Lowry Lab/UCLAScientists at the Eli and Edythe Broad Center of Regenerative Medicine and...
Post
B-cells hold promise for treating glioblastoma
September 23, 2024 by Olivia Dimmer, Northwestern University Quantitative analysis of BCR-seq data. Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI177384Harnessing the body’s B-cells to fight tumors may be a promising treatment for glioblastoma, according to a Northwestern Medicine study recently published in the Journal of Clinical Investigation. Glioblastoma, one of the most complex and...
Post
Toxic glass kills 99% of bone cancer without harming healthy cells
By Michael IrvingSeptember 18, 2024 Bioactive glass laced with toxic metal shows promise in treating bone cancer Depositphotos Scientists have demonstrated a new potential treatment for bone cancer. A bioactive glass laced with a toxic metal was able to kill up to 99% of the cancer without harming healthy cells, and could even help regrow...
Post
Team discovers role of ferroptosis in combating breast cancer resistance
September 13, 2024 by Jeni Bushman, University of Illinois at Urbana-Champaign Transmission electron microscopy (TEM) analyses to monitor cell morphology and mitochondrial integrity. Credit: Breast Cancer Research and Treatment (2024). DOI: 10.1007/s10549-024-07420-9An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for drug-resistant breast cancer. Their findings, published...