by Tulane University aP-T-vant immunized mice eliminated B. pertussis from the lung and nasopharynx. Credit: npj Vaccines (2024). DOI: 10.1038/s41541-024-00990-1 As whooping cough cases rise in the U.S., a new nasal vaccine developed by Tulane University may hold the key to reducing the spread of the highly contagious respiratory disease. Current pertussis vaccines are widely used and effective...
Category: <span>Vaccines</span>
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New COVID vaccine booster: Q&A on why you should wait
by Lisa M. Krieger, The Mercury News Credit: Unsplash/CC0 Public Domain Yes, older Americans should get yet another COVID shot—but if you have already gotten the latest version, there’s no rush. The Centers for Disease Control and Prevention last week said that people 65 and older or who are immunocompromised need a second dose of...
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Study finds RSV vaccine highly effective in protecting older adults against severe disease, hospitalization and death
Credit: CC0 Public Domain A multi-state study, published in The Lancet, is one of the first real world data analyses of the effectiveness of the RSV—short for respiratory syncytial virus—vaccine. VISION Network researchers report that across the board these vaccines were highly effective in older adults, even those with immunocompromising conditions, during the 2023–24 respiratory disease season, the...
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mRNA vaccines for disease outbreaks can be synthesized in less time with new technique
The phosphorylation reagent with a nitrobenzyl hydrophobic tag allows production of high purity fully chemically synthesized mRNA and transcriptionally synthesized cyclic mRNA. Credit: Reiko Matsushita In an era where viral outbreaks can escalate into global pandemics with alarming speed, the ability to quickly develop new vaccines has become crucial. However, the speed of vaccine production...
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Mpox vaccine is safe and generates a robust antibody response in adolescents
NIH clinical trial addresses knowledge gap on vaccine use in adolescent populations Reports and Proceedings NIH/National Institute of Allergy and Infectious Diseases image: Colorized transmission electron micrograph of mpox virus particles (light green) found within VERO E6 cells (teal). The virus particles are in various stages of maturity, which accounts for differences in shape. Captured...
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Newly discovered COVID vaccine targets may last longer
Workflow for the generation of SARS-CoV-2-derived HLA I and HLA II immunopeptidome data. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-51959-6 Melbourne researchers have discovered more than 200 new vaccine target candidates from the COVID-19 virus, SARS-CoV-2, that could lead to the development of vaccines with a longer lasting broader immunity than existing vaccinations. In a paper published in the journal Nature...
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New model shows potential for human papillomavirus vaccination switch to 1-dose gender-neutral approach
Canadian vaccination programs could switch to a 1-dose gender-neutral human papillomavirus (HPV) vaccination approach and eliminate cervical cancer, suggests new modeling in Canadian Medical Association Journal. “Our results have important policy implications in Canada, and in other similar high-income countries evaluating whether to switch to 1-dose HPV vaccination,” writes Dr. Marc Brisson, a full professor at...
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Influenza vaccine protects children from infection and hospitalization for the disease, Spanish study shows
An article published in Eurosurveillance has demonstrated that Spain’s influenza vaccination campaign for children aged 6–59 months during the 2023/24 season was effective in preventing acute respiratory infections (ARI) and hospitalization, as vaccination was recommended for this age group at the national level for the first time. In the context of Child Health Day 2024, this research emphasizes that...
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This season’s flu vaccine cuts risk of hospitalization by almost 35%, finds report
The Southern Hemisphere’s flu season is winding down, and new data shows this year’s flu shot was 34.5% effective in keeping folks there who got influenza from needing hospital care. Most (68.3%) of those sent to hospital had the A(H3N2) strain of flu, according to the report from the U.S. Centers for Disease Control and...
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Study demonstrates that mpox vaccine antibody responses wane within a year
Mpox Virus Particle Colorized transmission electron micrograph of an mpox virus particle (yellow and red) found within an infected VERO E6 cell (blue), cultured in the laboratory. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID/CC0 Public Domain A study led by researchers at Beth Israel Deaconess Medical Center...