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Revolution or mirage? Controversy surrounds new Alzheimer’s drugs
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Revolution or mirage? Controversy surrounds new Alzheimer’s drugs

September 20, 2024 Credit: Unsplash/CC0 Public DomainTwo new drugs, the first capable of slowing down the debilitating progression of Alzheimer’s disease, have become embroiled in one of the biggest medical controversies in recent years. For their defenders, the drugs lecanemab and donanemab represent the first real chance to fight the disease after decades of research—for...

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New Diagnostic Criteria for Alzheimer’s Will Change Practice

Neil Skolnik, MD DISCLOSURES | September 10, 2024 This transcript has been edited for clarity. I’m Dr Neil Skolnik and today I’m going to talk about the Revised criteria for diagnosis and staging of Alzheimer’s disease (AD) from the Alzheimer’s Association Workgroup. This is a big deal that will fundamentally change the way we will...

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Is Routine Colonoscopy Warranted for Appendicitis Patients?

Miriam Davis September 22, 2023 Appendicitis is widely known to be associated with colon cancer. Consider a 2020 meta-analysis finding that appendicitis increases the risk of colon cancer 10 fold. It is now standard practice for appendicitis patients to have preoperative imaging and intra-operative investigations to check for co-existing colon cancer. But should all appendicitis...

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Dementia Deemed Highly Preventable: Here’s How

JoAnn E. Manson, MD, DrPH DISCLOSURES | August 14, 2024 Hello. This is Dr JoAnn Manson, professor of medicine at Harvard Medical School and Brigham and Women’s Hospital. I’d like to talk with you about a new report on the preventability of dementia that is both exciting and paradigm-shifting. The new study, published in The...

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Did Statin Decision-Making Just Get Harder?

John M. Mandrola, MD DISCLOSURES | August 08, 2024 The new American Heart Association Predicting Risk of cardiovascular disease EVENTs (PREVENT) equation outperforms the standard pooled cohort equation (PCE). But there is a problem. A big one, actually. The new score incorporates kidney function and social situation, and it eliminates race from the estimate. It...

Beers Criteria Update for Medication Use in Older Adults
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Beers Criteria Update for Medication Use in Older Adults

MDedgeCOMMENTARY Linda Girgis DISCLOSURES | August 30, 2024 Linda Girgis, MD Primary care physicians know the complexities of treating older patients, from increased complications from medications and procedures to comorbidities stemming from having multiple medical conditions. The Beers Criteria were established by the American Geriatrics Society as a guide for physicians about medications that may...

How Old Is Too Old for a Colonoscopy?
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How Old Is Too Old for a Colonoscopy?

Medscape Medical News > Features Carolyn Crist August 26, 2024 Colonoscopy remains the gold standard method for detecting colorectal cancer (CRC) and removing precancerous polyps. The recommended age for CRC screening in the United States spans 45-75 years, with the benefits of colonoscopy diminishing considerably after this point. Older adults are much more likely to...

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Can Dry Fasting Help With Metabolic Disorders, Diabetes?

Medscape Medical News > Features Marilynn Larkin August 14, 2024 Dry fasting, the practice of going without food and water, has enthusiastic advocates on TikTok, X, YouTube, and other social media platforms. Devotees claim a wide range of health effects, but medical professionals advise caution to ensure that the practice does more good than harm,...

Primary Care: Re Carpe Your Diem
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Primary Care: Re Carpe Your Diem

Medscape Medical News > Features Primary Care: Re Carpe Your DiemAnn Thomas, MD, MPH August 19, 2024 William Fox, MD, a self-described “dinosaur,” works in an independent internal medicine practice with two other physicians in Charlottesville, Virginia. He is rarely able to accept new patients, and when he does see one, they often have to...

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