by Gillian Rutherford, University of Alberta Altered metabolomic profile in SARS-CoV-2 infected individuals. Credit: Frontiers in Immunology (2024). DOI: 10.3389/fimmu.2024.1341843A University of Alberta research team brings together immunologists, virologists, rheumatologists and metabolomics experts in an effort to discover exactly what is ailing the sickest long COVID patients and find treatments for them. In research recently published...
by McMaster University Image depicting UMAP of mass cytometry data analyzing human B cell subsets. Credit: Depiction generated by David R. Glass, project lead by Joshua F.E. Koenig, Peter Sejer Andersen, Niels Peter H. Knudsen, Allyssa Phelps, and Kelly Bruton.Researchers with McMaster University and Denmark-based pharmaceutical company ALK-Abello A/S have made a groundbreaking discovery: a new...
by Robin Foster Credit: Unsplash/CC0 Public DomainWhen getting vaccines, switching arms for each dose may produce greater immunity than having the jabs delivered into the same arm. That’s the finding from a new study in the Journal of Clinical Investigation that looked at the first two doses of COVID vaccines. Those who alternated arms showed...
by Northwestern University Credit: Pixabay/CC0 Public DomainScientists at the UC San Francisco (UCSF) and Northwestern Medicine may have found a way around the limitations of engineered T cells by borrowing a few tricks from cancer itself. By studying mutations in malignant T cells that cause lymphoma, they zeroed in on one that imparted exceptional potency to...
by American Society for Microbiology Credit: Pixabay/CC0 Public DomainDuring pregnancy, a woman’s immune system changes dramatically but researchers don’t yet understand all the underlying mechanisms. A new study shows how the gut microbiota may play a role. In a paper published in mSystems, researchers in China report that during pregnancy, changes in levels of cytokines—immune system...
by Anglia Ruskin University Credit: Pixabay/CC0 Public DomainPromising trial results indicate that a new type of cell therapy could improve the prognosis of those who are critically ill with acute respiratory distress syndrome (ARDS) resulting from severe COVID-19. The findings are published in the journal Nature Communications. Professor Justin Stebbing of Anglia Ruskin University (ARU) is...
Peer-Reviewed Publication MONASH UNIVERSITY Australian researchers have worked out how to fix a defect that causes lupus, and hope their world-first discovery will offer effective long-term treatment. Published in Nature Communications, the Monash University-led study found a way to reprogram the defective cells of lupus patients with protective molecules from healthy people. Using human cells,...
by Kim North Shine, University of Michigan Credit: Unsplash/CC0 Public DomainFirst boosters, second boosters, monovalent, bivalent. Just like the SARS-CoV-2 virus strain, the vaccines to combat the virus are always changing—and perhaps confusing. With the goal of better understanding the variety of vaccines and the methods used globally to study vaccines’ effectiveness, a group of University...
by Queen Mary, University of London Credit: Pixabay/CC0 Public DomainResearchers from Queen Mary University of London have found that the molecule RvT4 enhances the body’s natural defenses against atherosclerosis (hardening of the arteries) in patients with rheumatoid arthritis. Studies in mice undertaken by researchers from Queen Mary University of London’s William Harvey Research Institute and Center...
by McMaster University Credit: Pixabay/CC0 Public DomainFor years, there has been a long-held belief that acute viral infections like Zika or COVID-19 are directly responsible for neurological damage, but researchers from McMaster University have now discovered that it’s the immune system’s response that is behind it. The research, published on Feb. 5, 2024, in Nature Communications,...
