In an industrial collaboration project, TU Wien has developed a medication that can alleviate or even completely eliminate the symptoms of celiac disease. It should be available as early as 2021. Only the part of the antibody (left) that binds to gluten is needed to create a product, which does not trigger an immune response....
Category: <span>Immunology</span>
Post
Experimental vaccine shows promise in preventing TB
(HealthDay)—Tuberculosis remains the most lethal of infectious diseases worldwide, killing more than 1.6 million people a year. But researchers say a new vaccine might prevent half of full-blown illnesses in infected people who receive the shot. “We found that the incidence of pulmonary tuberculosis was significantly lower” for people who got the experimental vaccine, called M72/AS01, than for people...
Post
Breakthrough in schizophrenia identifies importance of immune cells
Researchers from NeuRA and UNSW have made a major discovery in schizophrenia research that could open doors to new treatments, research, and therapies. In one of the biggest breakthroughs in schizophrenia research in recent times, Professor Cynthia Shannon Weickert from Neuroscience Research Australia (NeuRA) and UNSW Sydney have identified immune cells in greater amounts in the brains of some...
Post
Immune response mechanism described for fate determination of T cells
This knowledge can aid vaccine development, treatment of infections and moderation of autoimmune disease UNIVERSITY OF ALABAMA AT BIRMINGHAM BIRMINGHAM, Ala. – After a pathogen infects the body, the immune system responds with a remarkable — and remarkably complicated — cascade of events. IMAGE: THIS IS CASEY WEAVER. Some immune cells, called lymphocytes, migrate to the...
Post
Mononuclear phagocytes can both promote and inhibit inflammation
Mononuclear phagocytes can both promote and inhibit inflammation. A Team from Ludwig-Maximilians-Universitaet (LMU) in Munich has now shown that individual phagocytes in the central nervous system can play both roles, sequentially adopting different phenotypes with distinct functions. Mononuclear phagocytes, which recognize, engulf and digest damaged and infected cells, form an important arm of the innate...
Post
Biochemists described a new mechanism for autoimmunity suppression
RUDN biochemists suggested a new mechanism by which the human body prevents the development of autoimmune diseases, allergies, and implant rejection. They report that regulatory T-cells are able to suppress the reproduction of autoimmune cells. The work was published in Molecular Immunology. Plastic plate with a medium for cell growth. Credit: Dmitry Zhdanov The ability of...
Post
The irresistible CCL17
Researchers at the University of Bonn discover a new role for the allergy driver: It influences signal transmission in the brain The chemotactic protein CCL17 attracts immune cells to where they are currently needed. Doctors have long known: A high level of this substance in the body indicates an allergic reaction. A team of scientists led...
Post
Researchers testing new brain cancer vaccine
Rush University Medical Center is part of a new clinical trial testing whether an experimental vaccine can help patients’ immune systems stop the spread of glioblastoma—an aggressive form of brain cancer with very few current treatment options. Glioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0 Led by neuro-oncologist Clement Pillainayagam, MD, the phase II clinical trial...
Post
Enhancing immune checkpoint inhibitor therapy using treatment combination
A combination of a novel inhibitor of the protein CK2 (Casein kinase 2) and an immune checkpoint inhibitor has dramatically greater antitumor activity than either inhibitor alone, according to research from The Wistar Institute that was published online in Cancer Research. Credit: The Wistar Institute Immune checkpoint inhibitors have been approved to treat several types...
Post
Immunotherapy could offer hope for some men with aggressive prostate cancers
A group of men with especially aggressive prostate cancer may respond unusually well to immunotherapy, a major new study reports. Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia The research offers the possibility of effective treatment for men with prostatecancer who currently die from their disease much more rapidly...