WEIZMANN INSTITUTE OF SCIENCE IMAGE: HUMAN LIVER TISSUE UNDER A MICROSCOPE. COMPARED TO HEALTHY DONORS (LEFT), TISSUE SAMPLES FROM PEOPLE WITH ACUTE LIVER FAILURE (CENTER, RIGHT) REVEAL A SIGNIFICANT INCREASE IN LEVELS OF THE MYC. Acute liver failure is a devastating, rapidly progressing disease that results in death in 80% of cases, unless an emergency...
By Rich Haridy, November 01, 2020 In a new study, mice with certain gut bacteria populations were found to be protected from the adverse effects of radiation We know radiation therapy is an aggressively toxic treatment methodology for fighting cancer. Gastrointestinal distress is a common side-effect but researchers are only now discovering exactly how the massive population...
AMERICAN GASTROENTEROLOGICAL ASSOCIATION Bethesda, MD (Oct. 1, 2020) — Today, the American Gastroenterological Association (AGA) released the first results from the NIH-funded AGA Fecal Microbiota Transplantation (FMT) National Registry, the largest real-world study on the safety and effectiveness of FMT. Published in Gastroenterology, the registry reported that FMT led to a cure of Clostridioides difficile (C. difficile) infection in...
The research reveals how transplanting those gut bacteria into other mice can cause changes to sleep patterns in the recipient mice. The study shows the gut microbiome is a major role player in sleep regulation, says David Gozal, chair of Child Health at the University of Missouri School of Medicine. This ultimately could translate into treatments that target the...
UNIVERSITY OF CALIFORNIA – RIVERSIDE IMAGE: RECONSTRUCTED MICROSCOPY IMAGE OF A BACTERIOPHAGE, WHICH IS A VIRUS THAT ATTACKS BACTERIA. Strictly speaking, humans cannot digest complex carbohydrates — that’s the job of bacteria in our large intestines. UC Riverside scientists have just discovered a new group of viruses that attack these bacteria. The viruses, and the...
UNIVERSITY OF MISSOURI-COLUMBIA IMAGE: DAVID GOZAL, MD, THE MARIE M. AND HARRY L. SMITH ENDOWED CHAIR OF CHILD HEALTH AT THE MU SCHOOL OF MEDICINE Obstructive sleep apnea (OSA) is a chronic sleep condition affecting more than one billion people worldwide. Evidence suggests OSA can alter the gut microbiome (GM) and may promote OSA-associated co-morbidities,...
by Katherine Fenz, Rockefeller University A cross section of the colon with enteric neurons highlighted. These neurons interface directly with gut microbes. Credit: Rockefeller University The 10 trillion bacteria living in your digestive system may not be human, but they seem to be as integral to your body as your heart or liver. A growing number...
by NIH/National Institute of Allergy and Infectious Diseases Inner elbow of a child with eczema before Roseomonas mucosa therapy (left) and after four months of treatment (right). An experimental treatment for eczema that aims to modify the skin microbiome safely reduced disease severity and increased quality of life for children as young as 3 years of...
by Children’s Hospital Boston Children’s Hospital tested PR1P in lung cells and mouse models of emphysema, they found that it protected VEGF from being degraded, prevented cell death, and protected the lung. Credit: Hao Wu, PhD, Boston Children’s Hospital Emphysema is a progressive, debilitating lung disease in which the lung’s breathing sacs, or alveoli, enlarge,...
ALBERT EINSTEIN COLLEGE OF MEDICINE July 30, 2020–(BRONX, NY)–A new study shows how chronic psychological stress leads to painful vessel-clogging episodes–the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations. The findings, made in mice, show that the gut microbiome plays a key role in triggering those episodes and reveals possible...
