MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN In recent years, brown fat has garnered increasing attention as the so-called good fat that can protect against obesity and associated health risks, like cardiovascular disease and diabetes. Brown fat is located in small pockets throughout the body and helps maintain body temperature in cold environments. It gets its...
Category: <span>Mitochondrial Protease Therapy</span>
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Team demonstrates ability to supercharge cells with mitochondrial transplantation
by Brian Bell, University of California, Irvine Researchers at the University of California, Irvine have shown that they can give cells a short-term boost of energy through mitochondrial transplantation. The team’s study, published today in the Journal of the American Heart Association, suggests that mitochondrial transplantation could one day be employed to cure various cardiovascular,...
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Unexpected insights into the dynamic structure of mitochondria
Publication in EMBO Reports HEINRICH-HEINE UNIVERSITY DUESSELDORF As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. Until now, it has been assumed that these functions underlie a static structure of mitochondrial membranes. Researchers at the Heinrich Heine University Düsseldorf (HHU) and the University of California...
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Researchers identify control of a mitochondrial protective mechanism
Mitochondria are known as the “powerhouses” of cells. However, under critical pathophysiological conditions, they can use cellular energy for self-preservation. This occurs when the operating mode of a molecular machine in the mitochondrial sheath becomes reversed. An international research group led by MedUni Vienna’s Center for Physiology and Pharmacology has now identified L-type calcium channels...
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Study provides new understanding of mitochondria genome, potential for new avenues of treatment for cancers
by University of Texas M. D. Anderson Cancer Center A study led by The University of Texas MD Anderson Cancer Center furthered understanding about mitochondria, the cell components known as the “powerhouse of the cell.” Knowing more about the genome is crucial given that mitochondria play important roles in tumorigenesis. Findings were published in the...
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Muscle weakness after sepsis linked to mitochondrial dysfunction
New findings may explain why humans experience muscle weakness after sepsis recovery, and suggest the need for novel treatments to improve muscle health ELIFE Damage to energy-producing mitochondria may underlie prolonged muscle weakness following a sepsis-like condition in mice, according to a new study published today in eLife. The findings may explain why humans struggle...
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Tracking inheritance of human mitochondrial DNA
This news or article is intended for readers with certain scientific or professional knowledge in the field. New insight into how genetic information stored in human mitochondria is passed from one generation to the next could have important implications for genetic counseling of women planning pregnancies, according to a study by researchers at Penn State...
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Molecular gatekeepers that regulate calcium ions key to muscle function
CHILDREN’S NATIONAL HOSPITAL Calcium ions are essential to how muscles work effectively, playing a starring role in how and when muscles contract, tap energy stores to keep working and self-repair damage. Not only are calcium ions vital for the repair of injured muscle fibers, their controlled entry into the mitochondria, the cell’s energy powerhouses, spells...
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Newly discovered protein is the permit to the powerhouse of cells
Medical University of South Carolina researchers report in Science Advances that they have discovered a protein, P17/PERMIT, that is key to recycling aging mitochondria and could be a connection between age-related diseases such as cancer and Alzheimer’s MEDICAL UNIVERSITY OF SOUTH CAROLINA Aging, and the mechanics behind it, remains one of the most closely guarded...
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Scientists liken mitochondria to Tesla battery packs
By Catharine Paddock, Ph.D. Fact checked by Isabel Godfrey New research reveals that mitochondria, the tiny powerhouses that live inside cells and give them energy, work more like a Tesla battery pack than the kind of battery that you put in a flashlight. Apart from red blood cells, all cells in the human body contain...