Neural processes involved in ADHD Date: October 30, 2019 Source: Okinawa Institute of Science and Technology (OIST) Graduate UniversitySummary:Researchers have investigated the actions of the drug in rats. Using dopamine cell recordings, electrochemical monitoring and computer modeling, they discovered a type of feedback loop that modulates dopamine levels in the rats’ brains in response to...
Category: <span>Neuroscience</span>
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Possible dementia vaccine closer after mice studies
Human trials tipped within two years FLINDERS UNIVERSITY A preventive treatment for dementia may proceed to clinical trials after successful animal testing. The US-led research is looking to develop effective immunotherapy via a new vaccine to remove ‘brain plaque’ and tau protein aggregates linked to Alzheimer’s disease. Recent success in bigenic mice models supports progression...
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What comes first, beta-amyloid plaques or thinking and memory problems?
by American Academy of Neurology The scientific community has long believed that beta-amyloid, a protein that can clump together and form sticky plaques in the brain, is the first sign of Alzheimer’s disease. Beta-amyloid then leads to other brain changes including neurodegeneration and eventually to thinking and memory problems. But a new study challenges that...
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Novel dementia vaccine on track for human trials within two years
By Rich Haridy A newly published study has described the successful results in mice of a novel vaccine designed to prevent neurodegeneration associated with Alzheimer’s disease. The researchers suggest this “dementia vaccine” is now ready for human trials, and if successful could become the “breakthrough of the next decade.” The new study, led by the...
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Some learning is a whole-brain affair, study shows
JOHNS HOPKINS MEDICINE Researchers at Johns Hopkins Medicine have successfully used a laser-assisted imaging tool to “see” what happens in brain cells of mice learning to reach out and grab a pellet of food. Their experiments, they say, add to evidence that such motor-based learning can occur in multiple areas of the brain, even ones...
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A prospective, multicentric study indicates a new feature of cluster headache attacks
by International Headache Society A prospective study recently published in the journal Cephalalgia, the official journal of the International Headache Society, extends the idea behind cluster headache chronicity. The study, entitled “Temporal changes of circadian rhythmicity in cluster headache”, was first-authored by Dr. Mi Ji Lee, from the Department of Neurology, Neuroscience Center, Samsung Medical...
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Early prevention of neuropathic pain
by Torsten Arndt, Fraunhofer-Gesellschaft An unpleasant tingling in the hands and feet, numbness, fuzzy and burning sensations—these symptoms may indicate a neuropathy, a disease of the nervous system. If the pain persists for several months, it is referred to as chronic pain. By then, it is very difficult to treat, and the available drugs often...
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Research identifies changes in neural circuits underlying self-control during adolescence
Penn study shows developing brain networks support cognition in youth UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA — The human brain is organized into circuits that develop from childhood through adulthood to support executive function–critical behaviors like self-control, decision making, and complex thought. These circuits are anchored by white matter pathways which coordinate the brain...
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Prospective memory key to performance of everyday life activities in multiple sclerosis
by Kessler Foundation Kessler Foundation researchers reported results of a study of deficits in prospective memory in individuals with multiple sclerosis (MS) that may contribute to difficulties with everyday life activities. The article, “Time-based prospective memory is associated with functional performance in persons with MS,” was epublished on September 23, 2019 by the Journal of the...
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Transcendental Meditation prevents abnormal enlargement of the heart, reduces chronic heart failure
MAHARISHI INTERNATIONAL UNIVERSITY A randomized controlled study recently published in Ethnicity & Disease in their Autumn 2019 Hypertension issue found that the Transcendental Meditation (TM) technique helps to prevent abnormal enlargement of the heart compared to health education (HE) controls. Also known as left ventricular hypertrophy (LVH), it can lead to chronic heart failure and...