By Elizabeth Cooney July 6, 2023 ADOBE Traumatic brain injury multiplies the risk of major depression eightfold. While the emotional trauma of whatever caused such deep damage may be understandable, from a blast in a war zone to a blow on the playing field, there’s a physiological component, too, that neuroscientists have long suspected but have...
Category: <span>Psychology & Psychiatry</span>
As psychedelics near approval, there’s no consensus on how they work
By Olivia Goldhill July 3, 2023 ADOBE DENVER — The founder of Field Trip, a chain of shuttered ketamine clinics currently facing insolvency, put forward an unexpected theory of how psychedelics work to treat depression last month. “The truth is, almost all of the effect of psychedelic-assisted therapy could be placebo,” said Ronan Levy, speaking at a five-day conference...
Schizophrenia is associated with somatic mutations occurring in utero, study shows
by Cell Press Schizophrenia-associated somatic copy number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions. Credit: Cell Genomics / Maury et al. As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. In...
New study disentangles the influence of depression and anxiety on spontaneous neural activity
by Viviana Greco July 2, 2023 in Anxiety, Depression, Neuroimaging Anxiety and depression are widespread mental health issues in our society. They often occur together and can increase the risk of developing other mental and physical health problems. Researchers are using neuroimaging studies to better understand the underlying causes of these disorders. However, most studies have...
A new model for predicting patterns of persistent negative thinking based on brain connectivity
by Institute for Basic Science Model development procedure. For the model development, the researchers first predefined 20 seed regions within the DMN. Then the variance of the dynamic connectivity (written as DCC in the figure) between each DMN seed region and 280 brain parcels was calculated from 84 participants. Using the variance of dynamic connectivity as...
DO 27% OF PATIENTS HAVE ‘COGNITIVE BIOTYPE’ OF DEPRESSION?
Cognitive tasks show that these patients have difficulty with the ability to plan ahead, display self-control, sustain focus despite distractions, and suppress inappropriate behavior. Imaging showed decreased activity in two brain regions responsible for those tasks. Because depression has traditionally been defined as a mood disorder, doctors commonly prescribe antidepressants that target serotonin (known as selective serotonin...
People with obsessive-compulsive disorder have an imbalance of brain chemicals – our discovery could mean a treatment breakthrough
Published: June 28, 2023 9.09am EDT Authors Trevor RobbinsProfessor of Neuroscience, University of Cambridge Barbara Jacquelyn SahakianProfessor of Clinical Neuropsychology, University of Cambridge Marjan BiriaResearch Fellow of Mental Health Neuroscience, UCL MRI brain scan. SpeedKingz/Shutterstock People often jokingly say they’ve “got a bit of OCD” (obsessive-compulsive disorder) if they are overly organised or tidy. But OCD is...
Lonely people process the world differently, study finds
Reviewed by Lily Ramsey, LLM Jun 28 2023 The Russian writer and philosopher Leo Tolstoy may have been onto something when he wrote the opening line of Anna Karenina: “Happy families are all alike; every unhappy family is unhappy in its own way.” A recent study published in Psychological Science and led by a scholar now at the...
SCIENTISTS GAVE A NAZI MDMA AND HE RENOUNCED RACISM
NEUROSCIENCE/BRAIN SCIENCE A white supremacist took the party drug MDMA as part of a controlled science experiment, the BBC reports, and it proved so life-changing that he dropped his racist, bigoted beliefs. “This is stuff you can’t really put into words, but it was so profound,” the now former white supremacist identified as Brendan told the broadcaster. “I...
USPSTF recommendation on screening for depression and suicide risk in adults
JAMA NETWORK Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends screening for depression in the adult population, including pregnant and postpartum persons and older adults. The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for suicide risk in the adult population, including pregnant and postpartum...