by Chinese Medical Journals Publishing House Co., Ltd. The loss of retinal ganglion cells (RGCs) is a prevalent characteristic of glaucoma and often the reason behind disease progression. Now, a team of researchers has utilized AI to identify a RIPK3 inhibitor with neuroprotective properties. Findings can shape the future of glaucoma treatment. Credit: Dr. Yuanxu...
Category: <span>Research Updates</span>
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Mini-tumors from circulating breast cancer cells offer new treatment insights
by German Cancer Research Center Credit: Unsplash/CC0 Public Domain Tumor cells circulating in the blood are the germ cells of breast cancer metastases. They are very rare and have not been propagated in the culture dish until now, which made research into therapy resistance difficult. ADVERTISING A team from the German Cancer Research Center (DKFZ), the...
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Surprising ‘two-faced’ cancer gene role supports paradigm shift in predicting disease
by Queen Mary, University of London Credit: Pixabay/CC0 Public Domain A genetic fault long believed to drive the development of esophageal cancer may in fact play a protective role early in the disease, according to new research published in Nature Cancer. This unexpected discovery could help doctors identify which individuals are at greater risk of developing cancer, potentially leading...
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Unlocking proteostasis: A new frontier in the fight against neurodegenerative diseases like Alzheimer’s
by Hebrew University of Jerusalem Credit: Pixabay/CC0 Public Domain Scientists have uncovered a powerful ally in the fight against neurodegenerative diseases: a nucleolar complex that plays a pivotal role in maintaining cellular health through protein homeostasis (proteostasis), by which cells maintain the balance and proper functioning of their proteins. By suppressing this complex, researchers have shown...
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Detecting disease with only a single molecule
Nanopore-based sensors could transform diagnosticsPeer-Reviewed Publication University of California – Riverside UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules. Since the molecules scientists want to detect — generally certain DNA or protein molecules —...
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Major breakthrough for ‘smart cell’ design
Rice lab pioneers assembly kit for synthetic sense-and-respond circuits in human cellsPeer-Reviewed Publication Rice University image: Xiaoyu Yang, a graduate student in the Systems, Synthetic and Physical Biology Ph.D. program at Rice, is the lead author on a study published in the journal Science.view more Credit: (Photo by Jeff Fitlow/Rice University) HOUSTON – (Jan. 3, 2025)...
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COULD AN EYE TEST SPOT SCHIZOPHRENIA?
JANUARY 2ND, 2025POSTED BY YALE (Credit: Getty Images) SHARE THIS ARTICLE You are free to share this article under the Attribution 4.0 International license. TAGS UNIVERSITY YALE UNIVERSITY Could complex beliefs like paranoia have roots in something as basic as vision? A new study finds evidence that they might. When completing a visual perception task, in which participants...
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The nose knows: Nasal swab detects asthma type in kids
by University of Pittsburgh Credit: Pixabay/CC0 Public Domain Researchers at the University of Pittsburgh have developed a nasal swab test for kids that diagnoses specific asthma subtype, or endotype. This non-invasive approach could help clinicians prescribe medications more precisely and pave the way for research toward better treatments for lesser-studied asthma types, which have been difficult...
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Blood test can predict how long vaccine immunity will last, study shows
by Stanford University Medical Center Summary of proposed mechanism for involvement of megakaryocytes in promotion of durability of antibody responses to vaccination. Credit: Nature Immunology (2025). DOI: 10.1038/s41590-024-02036-z, https://www.nature.com/articles/s41590-024-02036-z When children receive their second measles-mumps-rubella vaccine, around the time they start kindergarten, they gain protection against all three viruses for all or most of their lives. Yet the effectiveness...
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Microglia digest large Alzheimer’s plaques by spitting enzymes at them, preclinical study finds
by Katie Cottingham, Cornell University Graphical abstract. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.115052 Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer’s disease by latching on to them, forming a sort of external stomach and releasing digestive enzymes into the space, according to a preclinical study by Weill Cornell Medicine...