CHAMPAIGN, Ill. — In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells. In a new study published in the journal ACS Nano, researchers at the University of Illinois at Urbana-Champaign demonstrated that “nanostimulators” – nanoparticles...
BY DAVID MELAMED, PHD Seneca Biopharma announced that work is underway to advance NSI-566, its leading stem cell treatment candidate, into a Phase 3 study in people with amyotrophic lateral sclerosis (ALS). The decision followed a meeting with the US Food and Drug Administration (FDA), and is supported by data collected from a Phase 1...
Single cell cloning tells the story of abnormal cells UNIVERSITY OF HOUSTON Two internationally renowned stem cell experts have found an abundance of abnormal stem cells in the lungs of patients who suffer from Chronic Obstructive Pulmonary Disease (COPD), a leading cause of death worldwide. Frank McKeon, professor of biology and biochemistry and director of...
The 2020 Canada Gairdner International Award has been awarded to Elaine Fuchs for her discovery of the role of adult skin stem cells in homeostasis, wound repair, inflammation, and cancer. These insights have established a foundation for basic knowledge on how adult stem cells form, maintain, and repair tissues and have provided the groundwork for...
Highlights • IRBIT is required for homeostasis of the intestinal epithelium • IRBIT inhibition of RNR ensures proper intestinal stem cell differentiation • Suppression of RNR in intestinal stem cell progeny reverses age-related dysplasia SummaryThe maintenance of the intestinal epithelium is ensured by the controlled proliferation of intestinal stem cells (ISCs) and differentiation of their...
by University of North Texas Health Science Center When news of the coronavirus emerged from Wuhan, China, Kunlin Jin, Ph.D., and a team of international researchers quickly joined forces to fight the mysterious disease. Dr. Jin relied on his more than 20 years of knowledge about stem cells to work with an international team driven...
Reviewed by James Ives Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise establish contacts with nerves. Targeting tumor innervation could thus lead to new cancer therapies. Stem cells can...
by University of Zurich Stem cells can generate a variety of specific tissues and are increasingly used for clinical applications such as the replacement of bone or cartilage. However, stem cells are also present in cancerous tissues and are involved in cancer progression and metastasis. Nerves are fundamental for regulating the physiological and regenerative processes...
by Stanford University Medical Center Old human cells return to a more youthful and vigorous state after being induced to briefly express a panel of proteins involved in embryonic development, according to a new study by researchers at the Stanford University School of Medicine. The researchers also found that elderly mice regained youthful strength after...
POHANG UNIVERSITY OF SCIENCE & TECHNOLOGY (POSTECH) Early mortality of myocardial infarction (MI), one of fatal diseases, is about 30%. So, it is critical to have immediate and proactive treatment to prevent a heart attack. Contributing to developing an efficient treatment of this fatal disease, a research team from South Korea recently proposed an effective...
