By Michael Irving Stanford scientists may have found a way to essentially return older cells to a more youthful state. The adult cells are treated with a mix of proteins from early embryonic development, which removes many of the molecular signs of aging. The cells closely resembled younger ones, and in mouse tests, older animals...
JOHNS HOPKINS MEDICINE Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes. The findings from this experimental study,...
MAYO CLINIC ROCHESTER, Minn. — Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work. The study, published in NPJ Regenerative Medicine, finds that human cardiopoietic cells...
Although there have been advances in microsurgical procedures, options for treatment to restore prior function after peripheral nerve injury are still unavailable. Currently, autologous nerve grafting remains the favored therapy. However, experimental researchers recently have concentrated efforts on artificial constructs development, specifically to combine smart biomaterials and stem cells, with the aim of enhancing the...
by University of Connecticut A population of stem cells with the ability to generate new bone has been newly discovered by a group of researchers at the UConn School of Dental Medicine. In the journal Stem Cells, lead investigator Dr. Ivo Kalajzic, professor of reconstructive sciences, postdoctoral fellows Dr. Sierra Root and Dr. Natalie Wee,...
KU LEUVEN In the event of a bone fracture, fatty acids in our blood signal to stem cells that they have to develop into bone-forming cells. If there are no blood vessels nearby, the stem cells end up forming cartilage. The finding that specific nutrients directly influence the development of stem cells opens new avenues...
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE Mount Sinai researchers have discovered a way to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation, according to a study published on February 27 in Cell Stem Cell. The scarcity of blood-forming stem cells,...
by CORDIS The European Bank for induced Pluripotent Stem Cells (EBiSC) and CHDI Foundation have collaborated with Censo Biotechnologies to generate a cohort of 45 iPSC lines derived from Huntington’s disease gene-expansion carriers and associated controls. These new lines will be used to further investigate the mechanisms of HD progression and for the development of...
by University of York New research has deciphered how rogue communications in blood stem cells can cause leukaemia. The discovery could pave the way for new, targeted medical treatments that block this process. Blood cancers like leukaemia occur when mutations in stem cells cause them to produce too many blood cells. An international team of...
Publication in Scientific Reports HEINRICH-HEINE UNIVERSITY DUESSELDORF Researchers from the Institute for Stem Cell Research and Regenerative Medicine (ISRM) at the medical faculty of Heinrich Heine University-Duesseldorf under the directorship of Prof. Dr. James Adjaye have developed a protocol for the reproducible isolation and characterization of kidney stem cells, urine derived renal progenitor cells (UdRPCs)...
