by Baylor College of Medicine Led by researchers at Baylor College of Medicine, a study published in the journal Cell Stem Cell reveals a new mechanism that contributes to adult bone maintenance and repair and opens the possibility of developing therapeutic strategies for improving bone healing. “Adult bone repair relies on the activation of bone...
Category: <span>Stem Cell Therapy</span>
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Gene therapy is facing its biggest challenge yet
After finally gaining traction as a potential treatment for certain genetic disorders, gene therapy tackles the challenge of sickle-cell disease. Grajevis Bakatunkanda’s mother knew the signs: when her son lost interest in dinner, that meant the pain was on its way. It would strike, like clockwork, nearly every week. Soon the shy, skinny boy would...
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Genomic features of AML in patients over age 60 can predict success of stem cell transplant
Genomic profiles can be used to classify patients by risk of relapse after transplant DANA-FARBER CANCER INSTITUTE For older patients with acute myeloid leukemia (AML), the prospects for success of a stem cell transplant can often be predicted based on the particular set of genetic mutations within the tumor cells, investigators at Dana-Farber Cancer Institute...
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Case report: Stem cells a step toward improving motor, sensory function after spinal cord injury
by Susan Barber Lindquist, Mayo Clinic Stem cells derived from a patient’s own fat offer a step toward improving—not just stabilizing—motor and sensory function of people with spinal cord injuries, according to early research from Mayo Clinic. A clinical trial enrolled 10 adults to treat paralysis from traumatic spinal cord injury. After stem cell injection,...
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Omega-3 fatty acids’ health benefit linked to stem cell control, researchers find
by Stanford University Medical Center Credit: CC0 Public Domain For years, researchers have known that defects in an ancient cellular antenna called the primary cilium are linked with obesity and insulin resistance. Now, researchers at the Stanford University School of Medicine have discovered that the strange little cellular appendage is sensing omega-3 fatty acids in the diet, and that this...
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High-tech foam offers new tool for developing stem cells
Two Florida State University researchers are developing a high-tech material currently used in athletic equipment and prosthetics into a special tool to better develop stem cells. The work could improve drug screening, disease modeling, precision medicine, and cell therapy. FAMU-FSU College of Engineering researchers Yan Li, an associate professor in chemical and biomedical engineering, and...
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Ultrastructure of focal adhesion scaffold unveiled in human pluripotent stem cells
UNIVERSITY OF TURKU Focal adhesions are known as signalling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signalling cascades. However, focal adhesions remain unstudied in the context of human pluripotent stem cells. The research group from the Turku Bioscience Centre at the University of Turku in Finland...
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The role of Klumpfuss in intestinal cell differentiation
by Leibniz Institute on Aging Stem cells are essential for homeostasis and cell renewal in organs like skin, lung or intestine. During the course of life, their function decreases steadily, making this decline a main factor for the development of age-associated diseases. Researchers of the Leibniz Institute on Aging in Jena, Germany, and their colleagues of the...
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First-ever US clinical trial of engineered iPSC-derived cell therapy for blood cancer
by University of Minnesota Medical School A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer (NK) cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia (AML) and B-cell lymphoma. The...
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How Stem Cells Make Decisions
Posted Today This news or article is intended for readers with certain scientific or professional knowledge in the field. Pluripotency is a feature of stem cell populations in which individual cells must know a great deal about their surroundings. If you’re a human embryonic stem cell — and who among us hasn’t been — the G1 (“Gap 1”) phase of development is...