A man in England with multiple sclerosis can walk and dance for the first time in 10 years after receiving a stem cell transplant for the disease. Roy Palmer spent the last decade in a wheelchair without any feeling in his legs. He decided to undergo a procedure known as hematopoietic stem cell transplantation (HSCT) after seeing the results from a television program. Two days after receiving treatment, Palmer regained feelings in his legs. HSCT is still considered to be...
Category: <span>Stem Cell Therapy</span>
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Mouse study supports stem cell therapy for cerebral palsy
Neural stem cells can repair damaged parts of the brain and restore motor impairments in mice that display features of cerebral palsy, according to new research published in eNeuro. These results demonstrate the feasibility of using stem cells to address the underlying brain injuries responsible for this group of common movement disorders. The right common carotid artery of post-natal day 7 mice...
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Skeletal stem cells regress when tasked with extensive regeneration
Adult mouse skeletal stem cells in the jaw revert to a more developmentally flexible state when called upon to regenerate large portions of bone and tissue, according to a study by researchers at the Stanford University School of Medicine. The finding is the first to show that mammalian adult stem cells can march backward along...
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Stem cells control their own fate, making lab-grown tissues less effective
Understanding how stem cells interact with their surroundings could lead to better lab-grown tissues.Credit: Imperial College London Tissues grown in the lab from stem cells may fail to live up their therapeutic promise because the cells choose their own fate. For the last 20 years, scientists have worked to engineer tissues for use in a...
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“Spray-On Skin” from AVITA Medical Approved to Treat Serious Burns
AVITA Medical, a Valencia, California firm, won FDA approval for its remarkable RECELL Autologous Cell Harvesting Device for serious burns in adult patients. In preparation for treatment, a small healthy piece of the patient’s skin sample is taken, from which the so-called “Spray-On Skin” preparation is made. The process only takes 30 minutes, so it...
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Small molecule plays big role in weaker bones as we age
MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY AUGUSTA, Ga. (Sept. 18, 2018) – With age, expression of a small molecule that can silence others goes way up while a key signaling molecule that helps stem cells make healthy bone goes down, scientists report. They have the first evidence in both mouse and human mesenchymal stem...
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Scientists grow human esophagus in lab
Tiny organoids enable personalized disease diagnosis, regenerative therapies CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER CINCINNATI – Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids. Published in the journal Cell Stem Cell the study is the latest advancement from researchers at the...
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A joint effort to understand cartilage development
Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, MD, Ph.D., collaborated with colleagues at several institutions to provide new insights into how gene activity drives the...
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Genetic testing helps predict disease recurrence in myelodysplastic syndrome
A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders characterized by dysfunctional blood cells, according to new research at Washington University School of Medicine in St. Louis. Such a practice could help doctors identify patients...
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Family tree of blood production reveals hundreds of thousands of stem cells
Adult humans have many more blood-creating stem cells in their bone marrow than previously thought, ranging between 50,000 and 200,000 stem cells. Researchers from the Wellcome Sanger Institute and Wellcome—MRC Cambridge Stem Cell Institute developed a new approach for studying stem cells, based on methods used in ecology. Credit: CC0 Public Domain The results, published today (5...