Such basic research supports the goal of using stem cells in therapy, where an important hurdle is efficient differentiation BIRMINGHAM, Ala. – The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem...
Category: <span>Stem Cell Therapy</span>
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Type 1 diabetes: Could modified blood stem cells lead to a cure?
Increasing levels of a certain protein in blood stem cells so that the immune system stops attacking insulin cells in the pancreas could be a way to halt type 1 diabetes, according to a new study reported in Science Translational Medicine. Scientists may have devised a way to reverse type 1 diabetes. Researchers led by those...
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Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury
Abstract Background Despite advances in neonatal care, bronchopulmonary dysplasia (BPD) remains a significant contributor to infant mortality and morbidity. While human amnion epithelial cells (hAECs) have shown promise in small and large animal models of BPD, there is scarce information on long-term benefit and clinically relevant questions surrounding administration strategy remain unanswered. In assessing the...
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Stem Cell Therapy Shows Promise for Common Cause of Blindness
Two studies show cell-based treatment is safe in patients with dry macular degeneration, with one showing improved vision NEW ORLEANS, Nov. 14, 2017 /PRNewswire/ — Results from two early clinical trials show that it may be possible to use human embryonic stem cells as treatment for the dry form of macular degeneration, according to presentations given today at...
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Understanding the Berlin patient’s unexpected cure
PORTLAND, Ore. — A decade ago, the medical world was shocked when a patient in Berlin, Germany, had been declared free of HIV after receiving a stem cell transplant to treat cancer. Doctors have repeatedly tried to replicate the result, but this HIV cure has evaded other patients so far. Dr. Jonah Sacha and colleagues...
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Induced pluripotent stem cells show astrocyte-neuron impact on brain pathology in autism
Using human induced pluripotent stem cells (iPSCs) to model autism spectrum disorder (ASD), researchers at the University of São Paulo, Brazil and University of California, San Diego have revealed for the first time that abnormalities in the supporting cells of the brain, called astrocytes, may contribute to the cause of the disorder. The findings, published...
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Researchers report findings on the effects of fat on stem cells
From left, Ilya Levental, Joseph Lorent, Allison Skinkle and Kandice Levental at the Laboratory of Membrane Biology at UTHealth’s McGovern Medical School. Skinkle, a Rice senior, began working in the lab as a freshman. You really are what you eat—especially when it comes to fats, according to a study this week in the journal Science...
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Study led by MIT Portugal faculty and alumni finds how to increase the survival time of stem cells
A team of researchers from the Faculty of Medicine at the University of Coimbra, led by Dr. Lino Ferreira, MIT Portugal Program Faculty and researcher at the Center for Neuroscience and Cell Biology (CNC) in collaboration with Langer Lab at MIT (USA), has developed a new technology, which is promising to understand and treat ischemic...
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How drinking affects brain stem cells
We all know that too much alcohol is bad for us, but do we know what it actually does to our brains? New research suggests that long-term, heavy alcohol consumption kills off brain stem cells, which play a key role in supporting healthy cognitive function. Habitual drinking damages the brain, but what does it do to...
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Pluristem Enters into Agreement with Tel Aviv Sourasky Medical Center to Conduct Phase I/II Trial in Steroid-Refractory Chronic GvHD
Tel Aviv Sourasky Medical Center will act as the sponsor of the study PLX-PAD cells have demonstrated efficacy in preclinical models of GvHD HAIFA, Israel, Nov. 06, 2017 (GLOBE NEWSWIRE) — Pluristem Therapeutics Inc. (NASDAQ:PSTI) (TASE:PSTI), a leading developer of placenta-based cell therapy products, today announced that it has signed...