Monkeys show reduced Parkinsonian symptoms following a donor-matched iPS cell-based therapy. One of the last steps before treating patients with an experimental cell therapy for the brain is confirmation that the therapy works in monkeys. Today, scientists at the Center for iPS Cell Research and Application (CiRA), Kyoto University, Japan, report monkeys with Parkinson’s...
Category: <span>Stem Cell Therapy</span>
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Fetal membranes may help transform regenerative medicine
A new review looks at the potential of fetal membranes, which make up the amniotic sac surrounding the fetus during pregnancy, for regenerative medicine. Fetal membranes have been used as biological bandages for skin grafts as well as for serious burns. They may also have numerous other applications because they contain a variety of stem cells, which might...
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Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
Highlights hPSC-derived photoreceptors express markers in a pattern similar to human development 2D/3D differentiation protocol generates sufficient cones for transplantation hPSC-derived cones incorporate into the adult retina following transplantation Summary Transplantation of rod photoreceptors, derived either from neonatal retinae or pluripotent stem cells (PSCs), can restore rod-mediated visual function in murine models of inherited blindness....
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Scientists devise ‘promising’ new stem cell treatment that has the ‘potential to cure Parkinson’s disease’ and stop tremors
In trials on laboratory monkeys, researchers were able to restore nerve cells In humans, the disease causes a loss of neurons, which affects movement Experts hailed the findings of the Japanese study to be ‘extremely promising’ A pioneering new stem cell treatment with the ‘potential to cure Parkinson’s disease’ has been crafted by researchers. In...
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Upon prolonged irradiation, human stem cells’ defenses are activated
Researchers from several Russian institutes, including MIPT, have found out how prolonged exposure to ionizing radiation affects human stem cells. They discovered that it causes a cell cycle delay, which leads to faster repairs of radiation-induced DNA double-strand breaks, with fewer errors. It is unclear what the health implications are, particularly how this affects the...
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Bacterial infection stresses hematopoietic stem cells
It has been thought that only immune cells would act as the line of defense during bacterial infection. However, recent research has revealed that hematopoietic stem cells, cells that create all other blood cells throughout an individual’s lifetime, are also able to respond to the infection. A collaboration between researchers from Japan and Switzerland found...
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Cell Therapy
About Cell therapy Cell therapy is a new official direction in medicine, based on the use of regenerative potential of the adult stem cells, aimed at the treatment of a variety of serious diseases, rehabilitation of patients after injuries and fighting with the premature signs of aging. Stem cells are also considered to be the promising...
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It’s not a rat’s race for human stem cells grafted to repair spinal cord injuries
More than one-and-a-half years after implantation, researchers at University of California San Diego School of Medicine and the San Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year after grafting. The findings are...
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Novel Stem Cell-Derived Model Created of Inflammatory Neurological Disorder
Brain-in-a-dish approach also showed two existing HIV drugs may be effective in rescuing mutated cells An international team of scientists, led by University of California San Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS). In doing so, the...
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Battling baldness by jumpstarting stem cells with lactate
Untreated mouse skin on the left versus skin that was treated with the drug UK5099 on the right If stem cells can do everything from growing skulls to generating new heart tissue, you’d think they’d also be able to help regrow hair on balding heads. In fact, they soon might be able to do just that. Last...