The truth came crashing home last year—a perfect storm of faulty genetics, the unrelenting march of age, and every athletic mishap I’ve ever stumbled through. After watching two kinds of arthritis stiffen my mother’s joints—leaving her with fingers pinched into what she called her “flippers” and staggering knee pain—I suppose it shouldn’t have been a...
Category: <span>Stem Cell Therapy</span>
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Mechanoresponsive stem cells to target cancer metastases through biophysical cues
A stiff punishment for tumors In patients, tumor cells do not grow in isolation, and their behavior is regulated not only by their own biology but also by interactions with their microenvironment. A key part of the microenvironment is the extracellular matrix, which typically has a greater stiffness in tumors than in surrounding normal tissues....
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Diffusion dynamics play an essential role in regulating stem cells and tissue development
Gradients of molecular signaling factors play an essential role in numerous events in embryonic development, from patterning limb and organ formation to the intricate shaping of the brain and neuroanatomical architecture. These gradients are a consequence of diffusion dynamics in tissues, and newly published work describes two vital aspects of these diffusion processes in tissue...
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University of Colorado Cancer Center Paper Refutes the Idea that Mutations Cause Cancer
Writing today in the journal Cancer Research, James DeGregori, PhD, deputy director of the University of Colorado Cancer Center offers evidence that it is forces of evolution driven by natural selection acting in the ecosystem of the body that, in the presence of tissue damage, allow cells with dangerous mutations to thrive. James DeGregori, PhD,...
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Gold injections: Can they treat rheumatoid arthritis?
Gold treatments were one of the earliest treatments for rheumatoid arthritis going back at least 75 years. There is no cure for rheumatoid arthritis (RA). Medications can slow down the disease, while complementary therapies can help people cope with the joint pain and stiffness, chronic fatigue, and other symptoms, such as low-grade fevers and dry skin and eyes. While gold...
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Dozens of US clinics are pushing dangerous unapproved stem cell therapy that promises to cure heart failure and costs thousands of dollars – but have no board-certified doctors
Researchers found 61 clinics are currently offering the treatment in the US They often charge thousands of dollars for procedures that are unapproved The procedures promise to cure heart failure, but only one center in the US has a board-certified cardiologist on staff Stem cell therapy isn’t approved to treat heart failure in the US,...
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What makes stem cells into perfect allrounders
Stem cells are considered biological allrounders because they have the potential to develop into the various body cell types. For the majority of stem cells, however, this designation is too far-reaching. Adult stem cells, for example, can replace cells in their own tissue in case of injury, but a fat stem cell will never generate...
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Lab-grown human colons change study of GI disease
Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell. The study is believed to be the first time human colon organoids have been successfully tissue engineered in this manner, according...
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One Gene Closer to Regenerative Therapy for Muscular Disorders
A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues. A study published June 1, by Nature Communications reports scientists identify a new gene essential to this process, shedding new light on possible new therapeutic strategies....
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Reducing inflammation protects stem cells during wound repair
Scientists have found a new way to protect stem cells from harsh inflammation during wound repair. In a study recently published in the journal Cytotherapy, researchers in India discovered that treating mice with a common anti-inflammatory drug called celecoxib promoted stem cell survival and healing when they injected the cells into wounds. The researchers, who are...