by Lori Solomon

Delayed Meniere disease (DMD) is associated with a higher prevalence of bilateral Meniere disease (MD) compared with classic MD (CMD), according to a study published online Oct. 15 in the European Archives of Oto-Rhino-Laryngology.

Suming Shi, from the Affiliated Eye and ENT Hospital at Fudan University in Shanghai, and colleagues investigated the clinical characteristics and endolymphatic hydrops manifestations in patients with DMD versus CMD. The analysis included 523 patients diagnosed with MD.

The researchers found that DMD prevalence was 6.1%. In DMD, bilateral MD was significantly more common (34.4 versus 14.5%). There was also more severe hearing loss in the first involved ear and more deteriorated vestibular-evoked myogenic potential in the contralateral ear among DMD patients. All affected ears had endolymphatic hydrops, with a higher contralateral endolymphatic hydrops proportion in DMD (34.4 versus 15.0%).

“DMD patients exhibit a higher prevalence of bilateral MD, more severe hearing loss, and greater contralateral endolymphatic hydrops compared to CMD patients,” the authors write. “Both subtypes share similar endolymphatic hydrops characteristics, suggesting common underlying mechanisms.”

More information: Suming Shi et al, Comparative analysis of classic and delayed Ménière’s disease: clinical characteristics and endolymphatic hydrops manifestations in an Asian cohort, European Archives of Oto-Rhino-Laryngology (2024). DOI: 10.1007/s00405-024-09025-w

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