Highlights A modified FOXO4-p53 interfering peptide causes p53 nuclear exclusion in senescent cells This FOXO4 peptide induces targeted apoptosis of...
Pill made from cellulose that absorbs water to swell up to 100 times its original size ‘can beat obesity’
The pill, called Gelesis100, is made from the vegetable extract cellulose It absorbs water and swells 100 times its original...
Rare benign tumors hold the ‘genetic recipe’ to combat diabetes
Rare benign tumors known as insulinomas contain a complicated wiring diagram for regeneration of insulin-producing human beta cells, which...
Team reveals molecular pathway of weight-controlling hormone
Scientists at NGM Bio have revealed deep insights into the role that a little-understood human hormone plays in regulating body...
Small intestine permeable peptides facilitate digestive tract absorption
Changing injected drugs into orally administered medications Biopharmaceuticals, medium- and high-molecular weight biologically active macromolecules, are not easily absorbed by...
New compound discovered in fight against inflammatory disease
A 10-year study by University of Manchester scientists for a new chemical compound that is able to block a key...
Highest adverse effect rates for three drugs in parkinson’s
(HealthDay)—Ropinirole, bromocriptine, and piribedil are associated with the highest incidence rates of adverse effects in Parkinson’s disease, according to a...
Drug combination may improve impact of immunotherapy in head and neck cancer
The combination therapy with TLR agonist and anti-PD-1 agent activates CD8+ T cells (red) in the tumors. Checkpoint inhibitor-based...
Serum Institute’s vaccine demonstrates significant efficacy against severe rotavirus
Pune, India (26 September 2017) – Results from a Phase 3 efficacy study in India of the Serum Institute of...
Immune cells produce wound healing factor, could lead to new IBD treatment
Specific immune cells have the ability to produce a healing factor that can promote wound repair in the intestine, a...