A healthy smile helps us live long, well and happy lives. But just like our bodies, our teeth succumb to age-related changes. So what happens to teeth as you age? And what can you do to ensure your smile lasts the distance?First, what are teeth made of? The tooth crown is covered by a hard...
Researchers from Osaka University have shown for the first time that damaged lysosomes are repaired by a process called microautophagy, which is essential for preventing aging Peer-Reviewed Publication OSAKA UNIVERSITY OVERVIEW: LYSOSOMES ARE REPAIRED BY ESCRT-DRIVEN MICROAUTOPHAGY, AND STK38 AND GABARAPS ARE KEY REGULATORS OF THIS PROCESS BY RECRUITING ESCRTS TO LYSOSOMES. THESE REGULATORS ARE...
by Justin Jackson , Medical Xpress Credit: CC0 Public Domain A research collaboration led by the University of Chinese Academy of Sciences, China, investigated the role of CHIT1, a protein associated with microglia, in aging. In a paper, “CHIT1-positive microglia drive motor neuron aging in the primate spinal cord,” published in Nature, the group identifies...
by Hokkaido University (Top) Cancer stem cells produce interleukin-6 (IL-6), which induces senescence in macrophages (Mφ). In turn, these produce arginase-1 and inactivate T cells. As a result, cancer cells are not killed by immune system cells, leading to tumor formation. (Bottom) Non-cancer stem cells do not produce IL-6. Macrophages do not age and T cells...
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Blood Factor Can Turn Back Time in the Aging Brain Platelets are behind the cognitive benefits of young blood, exercise and the longevity hormone klotho In a remarkable convergence, scientists have discovered that the same blood factor is responsible for the cognitive enhancement that results from young blood transfusion, the...
by Impact Journals LLC Outcomes of cell competition and control by selective destruction. Credit: Aging (2023). DOI: 10.18632/aging.204956 A new editorial paper titled “A novel theory of ageing independent of damage accumulation” has been published in Aging. The underlying cause or causes of aging are an enduring mystery, but in 1977, Kirkwood postulated that organisms might gain a...
by Chen Na, Chinese Academy of Sciences The intracellular mechanisms that support Rutin to function as a novel senomorphic agent in antiaging interventions. Credit: Dr. SUN’s group Since the discovery of hallmark features of senescence such as cell cycle arrest, apoptosis resistance and development of a senescence-associated secretory phenotype (SASP), efforts in understanding how senescent cells...
Published: July 6, 2023 8.27am EDT Author Ellen QuarlesAssistant Professor in Molecular, Cellular, and Developmental Biology, University of Michigan You likely know someone who seems to age slowly, appearing years younger than their birth date suggests. And you likely have seen the opposite – someone whose body and mind seem much more ravaged by time than...
By Dr. Liji Thomas, MD Jun 16 2023 Reviewed by Lily Ramsey, LLM Aging is a physiological function change affecting life at all scales, from cell to organ level. The drivers of this alteration are still largely unknown. However, shifts in the concentration of various molecules occur with aging. In this respect, an interesting new...
by Yale School of Public Health Credit: Unsplash/CC0 Public Domain A Yale School of Public Health study has found that older persons with mild cognitive impairment (MCI), a common type of memory loss, were 30% more likely to regain normal cognition if they had taken in positive beliefs about aging from their culture, compared to those...
