by Fatty Acid Research Institute Credit: CC0 Public Domain New research published today in Nutrients shows that people with a higher blood DHA level are 49% less likely to develop Alzheimer’s disease vs. those with lower levels, according to the Fatty Acid Research Institute (FARI). The study, led by Aleix Sala-Vila, Ph.D., suggested that providing extra dietary...
Tag: <span>Alzheimer</span>
Boosting one gene in the brain’s helper cells slows Alzheimer’s progression in mice
JANUARY 11, 2022 by Eric Hamilton, University of Wisconsin-Madison Fig. 1: Changes to the astrocyte translatome due to tau and amyloid pathology. A Schematic illustrating the crossing of MAPTP301S with the Aldh1l1_eGFP-RPL10a mouse. Astrocyte TRAP-seq performed on MAPTP301S vs. WT mice (both carrying the Aldh1l1_eGFP-RPL10a allele) at 3 months (B) and 5 months (C) in the spinal cord....
Drug codenamed NVG-291 could reverse the damage caused by Alzheimer’s
By STEPHEN ADAMS FOR THE MAIL ON SUNDAY PUBLISHED: 20:02 EDT, 2 October 2021 | UPDATED: 20:05 EDT, 2 October 2021 Scientists believe a revolutionary new drug that allows nerve cells to mend themselves could transform the treatment of Alzheimer’s. Unlike current treatments for the neurological condition, the drug, codenamed NVG-291, works by removing a natural barrier in the body...
USask-led research team shows alternate form of brain protein that causes Alzheimer’s actually protects against the disease
Findings from a new study on Alzheimer’s disease (AD), led by researchers at the University of Saskatchewan (USask), could eventually help clinicians identify people at highest risk for developing the irreversible, progressive brain disorder and pave the way for treatments that slow or prevent its onset. Image credit: Pixabay (Free Pixabay license) The research, published in the journal Scientific Reports in...
Lilly hails Alzheimer’s win with donanemab, boasting ‘significant slowing of decline’
by Ben Adams | Jan 11, 2021 7:55am The amyloid theory continues to grasp at life as Eli Lilly has unveiled new phase 2 data from donanemab that show it can help Alzheimer’s disease patients by clearing these plaques out of the brain. Lilly’s donanemab (once known as LY3002813), works an active immunotherapy designed to stimulate the patient’s...
Alzheimer’s disease: Anticipating end-of-life needs
By Mayo Clinic Staff As an Alzheimer’s caregiver, you might be your loved one’s most powerful voice. Make decisions that ensure dignity and comfort for your loved one. In the early stages of Alzheimer’s disease, caregivers often focus on keeping loved ones safe and comfortable. As the disease progresses, however, you might face difficult end-of-life...
Protein that can be toxic in the heart and nerves may help prevent Alzheimer’s
UT SOUTHWESTERN MEDICAL CENTER IMAGE: Abnormal deposits of the protein amyloid beta in the brain have been linked to Alzheimer’s disease. The above illustration reveals a potential way discovered by UTSW researchers to stop this process, leveraging the protective nature of the protein transthyretin (TTR) to identify a segment of this protein, TTR-S, that halts...
New study on circadian clock shows ‘junk DNA’ plays a key role in regulating rhythms
by Keck School of Medicine A depiction of the double helical structure of DNA. Its four coding units (A, T, C, G) are color-coded in pink, orange, purple and yellow. Credit: NHGRI If you’ve ever had a bad case of jet lag, you know how a disruption to your body’s circadian rhythm makes it difficult...
The brain pulsates differently in people suffering from Alzheimer’s disease
by University of Oulu In the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer’s disease. Pulsations in the brain appear as red signals at the frequency of the heartbeat. There is a clear difference in pulsations in the brains of healthy people and people with Alzheimer’s. Credit: Oulu Functional...
Alzheimer ‘tau’ protein far surpasses amyloid in predicting toll on brain tissue
Tau PET brain imaging could launch precision medicine era for Alzheimer’s disease UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Brain imaging of pathological tau-protein “tangles” reliably predicts the location of future brain atrophy in Alzheimer’s patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and...