Study of people with Alzheimer’s found 81 per cent had diabetes or prediabetes Research found cheap diabetes drugs may be able to slow progress of disease The link between diabetes and Alzheimer’s was found by studying brain cells Prof Wharton said insulin resistance could be ‘targeted to improve brain health’ By JO MCFARLANE FOR THE MAIL...
Tag: <span>Alzheimer’s disease (AD)</span>
Study hints at early sign of Alzheimer’s degeneration
by Maggie MacLellan, University of Western Ontario BrainsCAN researchers examined an area in the brain’s subcortical region called the basal forebrain that includes cholinergic neurons. These neurons are known to be severely damaged by Alzheimer’s disease. Credit: University of Western Ontario Researchers have moved one step closer to identifying targets for brain degeneration that occur...
Exploring how lipids and cholesterol relate to Alzheimer’s
by Lorena Anderson, University of California Credit: iStock/iLexx Professor Jing Xu and her students study extremely tiny motor proteins, but their work could make a huge contribution to the growing body of knowledge about Alzheimer’s and other diseases that progressively destroy brain tissue. Alzheimer’s disease is, so far, untreatable and incurable and is the sixth...
Alzheimer’s subtypes could affect future treatments, Mayo Clinic researchers find
MAYO CLINIC JACKSONVILLE, Fla. — Despite decades of scientific scrutiny, Alzheimer’s disease researchers have yet to work out its cause or treatment. Understanding what underlies its three distinct subtypes is thought to be a promising new research avenue. In a new study in JAMA Neurology, a team of neuroscientists at Mayo Clinic in Florida led...
Scientists link ‘hunger hormone’ to memory in Alzheimer’s study
UNIVERSITY OF TEXAS AT DALLAS Scientists at The University of Texas at Dallas have found evidence suggesting that resistance to the “hunger hormone” ghrelin in the brain is linked to the cognitive impairments and memory loss associated with Alzheimer’s disease (AD). The findings, based on observations of postmortem brain-tissue samples from Alzheimer’s patients and on experiments with a mouse model of AD, also...
Take steps to slow Alzheimer’s disease
by Pennsylvania State University Credit: Pennsylvania State University Alzheimer’s disease is the most common type of dementia. It slowly kills brain cells and is the fifth-leading cause of death for Americans age 65 and older. But contrary to popular belief, steps can be taken to slow it down. “People think Alzheimer’s is an entirely genetic disorder, but...
The Startling Link Between Sugar and Alzheimer’s
A high-carb diet, and the attendant high blood sugar, are associated with cognitive decline. In recent years, Alzheimer’s disease has occasionally been referred to as “type 3” diabetes, though that moniker doesn’t make much sense. After all, though they share a problem with insulin, type 1 diabetes is an autoimmune disease, and type 2 diabetes is a chronic...
Western bias in human genetic studies is ‘both scientifically damaging and unfair’
IMAGE: THIS IMAGE SHOWS THE DISTRIBUTION OF THE ANCESTRY OF INDIVIDUALS IN THE GWAS CATALOG AS OF JANUARY 2019. view more CREDIT: SIRUGO ET AL./CELL Despite efforts to include more diversity in research, people of European ancestry continue to be vastly overrepresented and ethnically diverse populations largely excluded from human genomics research, according to the authors of a commentary published...
New cell model of most common form of Alzheimer’s points to molecular causes, drug target
Harvard Medical School geneticists have created a new model-in-a-dish of sporadic Alzheimer’s disease, which accounts for more than 90 percent of Alzheimer’s cases and tends to strike people without a family history of the disease. Alzheimer’s disease. Credit: public domain The model marks the first time researchers have identified the same molecular abnormalities across multiple...
Antiepileptic drugs linked to higher risk of stroke in persons with Alzheimer’s disease
Antiepileptic drug use is associated with an increased risk of stroke among persons with Alzheimer’s disease, according to a new study from the University of Eastern Finland. The risk did not differ between old and new antiepileptic drugs. The results were published in the Journal of the American Heart Association. The risk of stroke was particularly elevated for the first three months of antiepileptic drug use and remained elevated after accounting for several chronic...
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