Tag: <span>Alzheimers</span>

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Flu shots may protect against the risk of Alzheimer’s, related dementias

Some studies have shown that vaccinated individuals appear less likely than the unvaccinated to develop dementia, although scientists aren’t sure why By Marlene Cimons – Washington PostOctober 25, 2023 at 7:00 a.m. EDT There are many good reasons to get a flu shot this fall, but here’s one that might surprise you: It could protect...

How a Candida infection could trigger mechanisms tied to Alzheimer’s
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How a Candida infection could trigger mechanisms tied to Alzheimer’s

A study in mice and cell cultures suggests that Candida albicans can infect the brain and trigger Alzheimer’s-like mechanisms. Image credit: Paul Campbell/Getty Images.Researchers have uncovered how a common fungus enters the brain and generates toxic proteins implicated in Alzheimer’s disease.By studying animal models, the team found that the fungus Candida albicans uses enzymes to...

This FDA-Approved Drug Slows Down Alzheimer’s. We Finally Know Why.
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This FDA-Approved Drug Slows Down Alzheimer’s. We Finally Know Why.

By REBECCA DYER A false-color scanning electron microscope image of a fibrin blood clot before and after the buildup of protofibrils. (Anurag Sharma/Pradeep Singh)Lecanemab received FDA approval in January after a phase 3 trial showed it slows cognitive decline in early-stage Alzheimer’s patients. While we know lecanemab clears amyloid beta buildup, it was unclear how...

Brains with Alzheimer’s disease have subnormal levels of important dietary antioxidants
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Brains with Alzheimer’s disease have subnormal levels of important dietary antioxidants

by Josh Meyer, Virginia Tech Credit: Unsplash/CC0 Public Domain Alzheimer’s disease is a progressive neurodegenerative disease estimated to affect 6 million Americans and 33 million people worldwide. Large numbers of those affected have not yet been diagnosed. A new study published in the Journal of Alzheimer’s Disease by a Virginia Tech Carilion School of Medicine faculty member shows...

Routine vaccines reduce Alzheimer’s risk by up to 30% in over 65s
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Routine vaccines reduce Alzheimer’s risk by up to 30% in over 65s

By Paul McClureAugust 17, 2023 New research found that the risk of developing Alzheimer’s disease in people aged 65 and over is significantly reduced if they’ve received routine vaccinations Depositphotos New research has found that people aged 65 and over who’ve received routine vaccinations are significantly less likely to develop Alzheimer’s disease. The study highlights the...

New study links changes in brain immune cells to Alzheimer’s
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New study links changes in brain immune cells to Alzheimer’s

by Michael McCarthy, University of Washington School of Medicine Photomicrograph of microglia (green) from a brain affected by Alzheimer’s disease shows enlarged lysosomes (pink), a sign the cell’s housekeeping duties have been disrupted. Credit: Lexi Cochoit, UW Neuroinflammation Lab Immune cells in the brains of people who had Alzheimer’s disease appear to behave differently than those...

Could a novel Alzheimer’s vaccine hold the key to prevent or treat the disease?
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Could a novel Alzheimer’s vaccine hold the key to prevent or treat the disease?

Share on PinterestCould a vaccine for Alzheimer’s disease be on the horizon? Henrik Sorensen/Getty Images Finding an Alzheimer’s disease treatment has proved challenging and controversial. A vaccine has been developed for a new target, a protein found in aging brain cells and blood vessels. Trialed in mice, it improves behavior and reduces levels of an...

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Novel vaccine targets inflamed brain cells in Alzheimer’s to modify the course of disease

 Reviewers’ NotesReviewed by Danielle Ellis, B.Sc.Jul 31 2023 A novel vaccine that targets inflamed brain cells associated with Alzheimer’s disease may hold the key to potentially preventing or modifying the course of the disease, according to preliminary research presented at the American Heart Association’s Basic Cardiovascular Sciences Scientific Sessions 2023. The meeting is in Boston, July...

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Oral Tau Inhibitor Continues to Show Promise in Alzheimer’s

Megan Brooks July 21, 2023 Treatment with an experimental oral tau aggregation inhibitor, hydromethylthionine mesylate (HMTM), led to a statistically significant reduction in an established biomarker of neurodegeneration in Alzheimer’s disease (AD) in the LUCIDITY phase 3 trial. Blood concentrations of neurofilament light chain (NfL) showed a 93% reduction in change over 12 months in participants receiving...

Enhanced light sensitivity may contribute to Alzheimer’s ‘sundowning,’ disease progression
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Enhanced light sensitivity may contribute to Alzheimer’s ‘sundowning,’ disease progression

UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: HEATHER FERRIS, MD, PHD, OF THE UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE’S DIVISION OF ENDOCRINOLOGY AND METABOLISM, FOUND THAT ENHANCED LIGHT SENSITIVITY MAY PLAY A KEY ROLE IN ALZHEIMER’S DISEASE. CREDIT: UVA HEALTH New Alzheimer’s research from UVA Health suggests that enhanced light sensitivity may contribute to “sundowning” – the worsening...