IMAGE: PICOMOLAR ANTIMALARIAL AGENT FROM A CHINESE MEDICINAL PLANT CREDIT: ©SCIENCE CHINA PRESS Dimeric sesquiterpenoids (DS), particularly the dimeric lindenane sesquiterpenoids dimers (DLS), featuring a basic scaffold by a [4 + 2] endo Diels–Alder reaction of two lindenane sesquiterpenoid monomers, are the characteristic components that occur mainly in the Chloranthus and Sarcandragenera. Shizukaol A from Chloranthus japonicus was the first...
Enrollment has begun in Phase 1 clinical trial to test the safety of a new investigational drug designed to treat malaria, as well as its effect on the human body. The first-in-human study is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and is...
A study involving researchers from The Australian National University (ANU) has found that platelets can attack and kill malaria parasites—reducing the number of parasites circulating in the blood. Credit: CC0 Public Domain The study, which has just been published in the prestigious journal Blood, was led by Associate Professor Brendan McMorran at ANU and Professor Nick Anstey at...
The case report discusses whether the patient’s autoimmune disease and its treatment could have contributed to achieving such a ‘striking’ response to treatment A cancer patient with advanced ovarian cancer had a “remarkable” journey to recovery that may be partially attributed to a treatment she received for a completely different disease, according to a case...
