Tag: <span>aortic stenosis</span>

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Treating asymptomatic aortic stenosis with TAVR linked to significant benefits

EARLY TAVR lead investigator Philippe Généreux, MD, announces his team’s findings in front of a packed audience at TCT 2024. Attendees cheered and roared with excitement as he revealed the study’s primary outcomes, an early sign that interventional cardiologists have been anticipating these results for quite some time.  Transcatheter aortic valve replacement (TAVR) is a safe,...

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Transcatheter aortic valve replacement in patients with systolic heart failure, aortic stenosis shows limited benefits

by Cardiovascular Research Foundation Credit: Unsplash/CC0 Public Domain Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS). Findings were reported today at TCT 2024, the annual scientific symposium of the Cardiovascular Research Foundation (CRF)....

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Early transcatheter aortic valve replacement can be beneficial for asymptomatic severe aortic stenosis patients: Study

by Cardiovascular Research Foundation Credit: Pixabay/CC0 Public Domain The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS). Findings were reported today at TCT 2024, the annual scientific symposium of...

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AI-Based Biomarker for Aortic Stenosis Found

Yale investigators from the cardiovascular medicine section have identified a new artificial intelligence (AI)-based video biomarker to identify those who might develop and have rapidly worsening aortic stenosis.This research was highlighted in a new paper, “A Multimodality Video-Based AI Biomarker For Aortic Stenosis Development And Progression,” published in JAMA Cardiology. More than 1.5 million people...

Rheumatoid arthritis tied to higher risk for aortic stenosis
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Rheumatoid arthritis tied to higher risk for aortic stenosis

by Lori Solomon Rheumatoid arthritis (RA) is associated with a higher risk for developing aortic stenosis, according to a study published online July 31 in JAMA Internal Medicine. Tate M. Johnson, M.D., from the VA Nebraska-Western Iowa Health Care System in Omaha, and colleagues examined the risk for incident aortic stenosis, aortic valve intervention, aortic stenosis-related death,...

Artificial intelligence identifies severe aortic stenosis from routine echocardiograms
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Artificial intelligence identifies severe aortic stenosis from routine echocardiograms

by European Society of Cardiology Micrograph showing calcific aortic stenosis, abbreviated CAS. Nephron/Wikimedia Commons, CC BY-SA 3.0 A novel artificial intelligence (AI) algorithm uses routine echocardiograms to identify aortic stenosis patients at high risk of death who could benefit from treatment. The late breaking research was presented in a Hot Line session on 28 August at ESC Congress 2022....

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Researchers identify potential therapeutic target for aortic stenosis

A Yale-led study provides new insights into the molecular and cellular development of supravalvular aortic stenosis (SVAS), a rare congenital heart defect caused by mutations or deletion of the elastin gene and characterized by narrowing of the aorta. The research, led by the Greif Lab in the Yale Cardiovascular Research Center, identified the role of the gene Notch3 in regulation...