Rheumatoid arthritis (RA) is an autoimmune disorder that occurs when the immune system mistakenly attacks the body’s tissues. Unlike the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the lining of the joints, causing painful swelling that can eventually result in bone erosion and joint deformity. Most RA patients are positive for anticitrullinated protein antibodies (ACPA), and these antibodies are...
Tag: <span>Arthritis</span>
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Flare-responsive hydrogel developed to treat arthritis
Arthritis flares – the unpredictable and often sudden worsening of arthritis symptoms—can be debilitating. These episodes can make the management of inflammatory arthritis, which includes rheumatoid arthritis and psoriatic arthritis, challenging for patients and physicians. But investigators at Brigham and Women’s Hospital have found that flares may also represent an important opportunity for improving treatment...
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Drug compound shows promise against rheumatoid arthritis
Scientists have designed a new drug compound that dials down inflammation, suggesting possible future uses against autoimmune disorders such as rheumatoid arthritis. The new inhibitor is more selective than other compounds designed to target the same inflammatory pathway, according to new research from Washington University School of Medicine in St. Louis. Such precision, along with...
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Chromosomal loop signatures could identify poor drug response in arthritis
Chromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequately to ‘anchor’ treatment drug methotrexate. New University of Glasgow research, published in the Journal of Translational Medicine, investigated whether differences in genomic architecture, as defined by a chromosome conformation signature (CCS) in blood taken pre-treatment from...
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Arthritis pill: Daily intake of new treatment halts disabling bone loss and damage
A DAILY pill which halts the disabling bone loss caused by osteoarthritis is being hailed as a new dawn in the treatment of the disease. The new drug has excited scientists after trials showed that after just six months it reduced bone damage around knee joints and also maintained cartilage thickness. It is the first...
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Studies reveal how shingles vaccine should be used in arthritis patients
New research indicates that the live varicella-zoster vaccine—which is given to protect against shingles—elicits robust immune responses in patients when administered several weeks prior to the start of treatment with the arthritis drug tofacitinib. The Arthritis & Rheumatology findings are encouraging because patients with rheumatoid arthritis have a higher risk of developing shingles than other adults, and...
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Women who take the Pill for several years ‘can cut their chance of suffering a common form of arthritis by a fifth’
Women who take the Pill are less likely to suffer arthritis, according to research Those who take the contraceptive pill for several years are statistically safer Study of 7,000 women in Sweden suggest pill takers 13% less likely to suffer Women who take the Pill are far less likely to suffer from a common form...
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New technology to manipulate cells could help treat Parkinson’s, arthritis, other diseases
A groundbreaking advancement in materials from Northwestern University could potentially help patients requiring stem cell therapies for spinal cord injuries, stroke, Parkinson’s disease, Alzheimer’s disease, arthritic joints or any other condition requiring tissue regeneration, according to a new study. “It’s important in the context of cell therapies for people to cure these diseases or regenerate...
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From the two-handled teapot to the tap turner: 10 gadgets to help you tackle arthritis
Around ten million Britons have some form of arthritis and live in pain Both osteoarthritis and rheumatoid arthritis can be extremely painful and worsen over time, leading to reduced strength and flexibility in the joints But a range of spcialist products and gadgets claim to ease the pain Around ten million Britons have some form...
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Arthritis may NOT be due to ‘wear and tear’: High-fibre diets reduce your risk of developing the condition by up to 61%
This is comparing those who have the highest daily fibre intake to the lowest High-fibre intakes also appear to prevent existing knee pain from getting worse Fibre is found in high amounts in brown rice, potato skins and other vegetables Arthritis UK warn more research is needed to assess high-fibre diets’ benefits High-fibre diets significantly...