WEILL CORNELL MEDICINE IMAGE: SYNAPSES ARE COMPOSED OF PRESYNAPTIC AND POSTSYNAPTIC TERMINALS (BLUE) AND ARE CONTACTED BY ASTROCYTES (PURPLE), A CRUCIAL NON-NEURONAL CELL TYPE. DEMENTIA-ASSOCIATED PROTEIN BUILDUP IN ASTROCYTES CAUSES ABNORMAL RELEASE OF IMMUNE FACTORS (ORANGE) THAT DISTURB PRESYNAPTIC FUNCTION AND CAUSE NEURONAL HYPERACTIVITY AND COGNITIVE DECLINE IN MICE CREDIT: ORIGINAL 3D BY BROKENGRID People...
