by Lori Solomon Long-term treatment of adolescents with moderate-to-severe atopic dermatitis (AD) with upadacitinib is safe and effective through 76 weeks, according to a study published online Oct. 23 in JAMA Dermatology. Amy S. Paller, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues evaluated the efficacy and adverse events of upadacitinib in adolescent patients with...
Tag: <span>atopic dermatitis</span>
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Atopic Dermatitis Control on Biologic Persists Over 3 Years
AMSTERDAM, Netherlands — For patients with atopic dermatitis (AD) who responded to the anti-interleukin (IL)-13 monoclonal antibody lebrikizumab in the pivotal trials, the level of response, including 90% skin clearance, has generally remained unchanged among those followed up for an additional 2 years, according to the latest data from an extension study. At the end...
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Dietary vitamin E may be protective against atopic dermatitis
August 30, 2024 by Lori Solomon Dietary intake of vitamin E may potentially lower the risk for atopic dermatitis, according to a study published online Aug. 9 in Skin Research & Technology. Siqing Wang, from the Beijing University of Chinese Medicine, and colleagues conducted a Mendelian randomization analysis to explore the causal relationship between dietary...
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FDA approves Zoryve for atopic dermatitis
JULY 12, 2024 by Lori Solomon The U.S. Food and Drug Administration has approved Arcutis Biotherapeutics’ Zoryve (roflumilast) cream, 0.15%, for the treatment of mild-to-moderate atopic dermatitis in adult and pediatric patients (ages 6 years and older). Zoryve is a once-daily, steroid-free cream that the company says will be available at the end of July....
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Experimental Topical Drug Shows Promise for Atopic Dermatitis, Psoriasis
Doug Brunk An experimental topical phosphodiesterase 4 (PDE4) inhibitor showed superior efficacy to vehicle in patients with mild to moderate atopic dermatitis (AD) and plaque psoriasis, results from a phase 2a study showed. PDE4 inhibitors are a promising therapeutic target for inflammatory diseases because “they can increase cyclic adenosine monophosphate levels and subsequently reduce the...
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New guidelines released for practitioners treating anaphylaxis and atopic dermatitis
by American College of Allergy, Asthma, and Immunology Credit: Unsplash/CC0 Public Domain Two new practice parameters from the Joint Task Force for Practice Parameters (JTFPP) offer evidence-based recommendations for the diagnosis and management of anaphylaxis and atopic dermatitis (AD) in pediatric and adult patients. The Joint Task Force is a partnership between the American College of...
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Gut-skin connection is key factor in atopic dermatitis, research review shows
by Julia Moióli, FAPESP Scientists believe the rising incidence of atopic dermatitis could be linked to alterations in gut microbiome composition, diet and lifestyle. Credit: James Heilman/Wikimedia Commons Atopic dermatitis (AD) is a chronic inflammatory skin disease whose main symptoms are redness, swelling, and itchy rashes. It is more common in people with a genetic predisposition....
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Study provides new insights for medication to treat atopic dermatitis
by National Jewish Health Credit: Unsplash/CC0 Public DomainPatients with atopic dermatitis, the most common inflammatory skin disease in the general population, often have vascular changes that lead to a loss of proteins in their skin and symptoms like oozing, bleeding, infection and redness. In a recent study, researchers at National Jewish Health tested a medication...
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Atopic dermatitis associated with schizophrenia, schizoaffective disorder
by Yale School of Medicine Atopic dermatitis. Credit: AfroBrazilian/Wikimedia Commons, CC BY-SA Atopic dermatitis (AD) is a chronic, inflammatory skin disorder that has well-established associations with depression and anxiety. A new Yale School of Medicine study, published in Archives of Dermatological Research, finds AD is also associated with increased risk for schizophrenia and schizoaffective disorder. Schizophrenia is...
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AI model helps atopic dermatitis patients diagnose complications and malignant diseases
by Tohoku University Images of skin lesions can vary significantly depending on the distance between the lesion and the imaging device. By minimizing the imaging bias caused by distance, the accuracy of skin lesion differentiation can be enhanced. Credit: Yuta Yanagisawa et al Atopic dermatitis skin lesions and the lesions produced by infectious complications of...