Doug Brunk An experimental topical phosphodiesterase 4 (PDE4) inhibitor showed superior efficacy to vehicle in patients with mild to moderate atopic dermatitis (AD) and plaque psoriasis, results from a phase 2a study showed. PDE4 inhibitors are a promising therapeutic target for inflammatory diseases because “they can increase cyclic adenosine monophosphate levels and subsequently reduce the...
Tag: <span>atopic dermatitis</span>
Post
New guidelines released for practitioners treating anaphylaxis and atopic dermatitis
by American College of Allergy, Asthma, and Immunology Credit: Unsplash/CC0 Public Domain Two new practice parameters from the Joint Task Force for Practice Parameters (JTFPP) offer evidence-based recommendations for the diagnosis and management of anaphylaxis and atopic dermatitis (AD) in pediatric and adult patients. The Joint Task Force is a partnership between the American College of...
Post
Gut-skin connection is key factor in atopic dermatitis, research review shows
by Julia Moióli, FAPESP Scientists believe the rising incidence of atopic dermatitis could be linked to alterations in gut microbiome composition, diet and lifestyle. Credit: James Heilman/Wikimedia Commons Atopic dermatitis (AD) is a chronic inflammatory skin disease whose main symptoms are redness, swelling, and itchy rashes. It is more common in people with a genetic predisposition....
Post
Study provides new insights for medication to treat atopic dermatitis
by National Jewish Health Credit: Unsplash/CC0 Public DomainPatients with atopic dermatitis, the most common inflammatory skin disease in the general population, often have vascular changes that lead to a loss of proteins in their skin and symptoms like oozing, bleeding, infection and redness. In a recent study, researchers at National Jewish Health tested a medication...
Post
Atopic dermatitis associated with schizophrenia, schizoaffective disorder
by Yale School of Medicine Atopic dermatitis. Credit: AfroBrazilian/Wikimedia Commons, CC BY-SA Atopic dermatitis (AD) is a chronic, inflammatory skin disorder that has well-established associations with depression and anxiety. A new Yale School of Medicine study, published in Archives of Dermatological Research, finds AD is also associated with increased risk for schizophrenia and schizoaffective disorder. Schizophrenia is...
Post
AI model helps atopic dermatitis patients diagnose complications and malignant diseases
by Tohoku University Images of skin lesions can vary significantly depending on the distance between the lesion and the imaging device. By minimizing the imaging bias caused by distance, the accuracy of skin lesion differentiation can be enhanced. Credit: Yuta Yanagisawa et al Atopic dermatitis skin lesions and the lesions produced by infectious complications of...
Post
Novel monoclonal antibody therapy shows promising results in patients with moderate to severe atopic dermatitis
Reviewed by Emily Henderson, B.Sc.Dec 12 2022 Patients with moderate to severe atopic dermatitis who participated in a clinical trial of rocatinlimab-;a novel, patient-tailored monoclonal antibody therapy-;showed promising results both while taking the drug and up to 20 weeks after the therapy was stopped, Mount Sinai researchers reported in The Lancet. The researchers said the results indicate...
Post
A serendipitous finding lends new insight into how atopic dermatitis develops
UNIVERSITY OF PENNSYLVANIA Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a new study pinpoints a cascade of inflammatory signaling that precedes the appearance of skin ulcers, shedding light on the...
Post
Upadacitinib in moderate to severe atopic dermatitis: high doses produce added benefit for adults
INSTITUTE FOR QUALITY AND EFFICIENCY IN HEALTH CARE Upadacinib is a new drug for the treatment of adults and adolescents aged 12 years and older with moderate to severe atopic dermatitis who are candidates for systemic therapy. In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) has now...
Post
New cell type in human skin discovered to contribute to inflammatory skin diseases like atopic dermatitis and psoriasis
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) SINGAPORE IMAGE: IMMUNOFLUORESCENCE LABELING OF HEALTHY AND PSORIATIC PATIENT SKIN. DOTTED LINE SHOWS THE DERMAL–EPIDERMAL JUNCTION. HLA-DR: GREEN, GLUT3 (SLC2A3): RED, AND DAPI: BLUE. SCALE BAR = 100 ΜM (LOW MAGNIFICATION) AND 10 ΜM (HIGH MAGNIFICATION). CREDIT: PLEASE CREDIT IMAGE TO A*STAR SINGAPORE IMMUNOLOGY NETWORK (SIGN) AND SKIN...
- 1
- 2