by Marissa Shapiro, Vanderbilt University Blocking MMP-13 reduces structural changes to mechanically injured joints. Top: Histological images of trichrome-stained sections showing that blocking MMP-13 protects cartilage structure and composition. Bottom: Micro-computed tomography imaging of mineralized tissues indicate that MMP-13 inhibition reduces unnatural mineralization and bone spurs in the mechanically injured joints. Red arrows and # symbols...
